TBX15-FMN2 Fusion FISH Probe
The TBX15-FMN2 Fusion FISH Probe is used to confirm a fusion of the TBX15 and FMN2 genes. The fusion of the TBX15 and FMN2 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TBX15-FMN2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TBX15-FMN2-20-RERE | 20 (40 μL) | 200 μL |
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| TBX15-FMN2-20-REOR | 20 (40 μL) | 200 μL |
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| TBX15-FMN2-20-REGO | 20 (40 μL) | 200 μL |
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| TBX15-FMN2-20-REGR | 20 (40 μL) | 200 μL |
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| TBX15-FMN2-20-REAQ | 20 (40 μL) | 200 μL |
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| TBX15-FMN2-20-ORRE | 20 (40 μL) | 200 μL |
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| TBX15-FMN2-20-OROR | 20 (40 μL) | 200 μL |
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| TBX15-FMN2-20-ORGO | 20 (40 μL) | 200 μL |
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| TBX15-FMN2-20-ORAQ | 20 (40 μL) | 200 μL |
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| TBX15-FMN2-20-GORE | 20 (40 μL) | 200 μL |
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| TBX15-FMN2-20-GOOR | 20 (40 μL) | 200 μL |
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| TBX15-FMN2-20-GOGO | 20 (40 μL) | 200 μL |
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| TBX15-FMN2-20-GOGR | 20 (40 μL) | 200 μL |
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| TBX15-FMN2-20-GOAQ | 20 (40 μL) | 200 μL |
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| TBX15-FMN2-20-GRRE | 20 (40 μL) | 200 μL |
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| TBX15-FMN2-20-GROR | 20 (40 μL) | 200 μL |
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| TBX15-FMN2-20-GRGO | 20 (40 μL) | 200 μL |
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| TBX15-FMN2-20-GRGR | 20 (40 μL) | 200 μL |
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| TBX15-FMN2-20-GRAQ | 20 (40 μL) | 200 μL |
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| TBX15-FMN2-20-AQRE | 20 (40 μL) | 200 μL |
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| TBX15-FMN2-20-AQOR | 20 (40 μL) | 200 μL |
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| TBX15-FMN2-20-AQGO | 20 (40 μL) | 200 μL |
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| TBX15-FMN2-20-AQGR | 20 (40 μL) | 200 μL |
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| TBX15-FMN2-20-AQAQ | 20 (40 μL) | 200 μL |
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TBX15 Gene Summary
This gene belongs to the T-box family of genes, which encode a phylogenetically conserved family of transcription factors that regulate a variety of developmental processes. All these genes contain a common T-box DNA-binding domain. Mutations in this gene are associated with Cousin syndrome.[provided by RefSeq, Oct 2009]
Gene Name: T-box 15
Chromosome: CHR1: 119425665 -119532179
Locus: 1p12
FMN2 Gene Summary
This gene is a member of the formin homology protein family. The encoded protein is thought to have essential roles in organization of the actin cytoskeleton and in cell polarity. This protein mediates the formation of an actin mesh that positions the spindle during oogenesis and also regulates the formation of actin filaments in the nucleus. This protein also forms a perinuclear actin/focal-adhesion system that regulates the shape and position of the nucleus during cell migration. Mutations in this gene have been associated with infertility and also with an autosomal recessive form of intellectual disability (MRT47). Alternatively spliced transcript variants have been identified. [provided by RefSeq, Jul 2017]
Gene Name: Formin 2
Chromosome: CHR1: 240255184 -240638489
Locus: 1q43
Gene Diseases
The TBX15 FMN2 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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