TBL1XR1-MCF2L2 Fusion FISH Probe
The TBL1XR1-MCF2L2 Fusion FISH Probe is used to confirm a fusion of the TBL1XR1 and MCF2L2 genes. The fusion of the TBL1XR1 and MCF2L2 genes has been associated with Esophageal Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TBL1XR1-MCF2L2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TBL1XR1-MCF2L2-20-RERE | 20 (40 μL) | 200 μL |
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| TBL1XR1-MCF2L2-20-REOR | 20 (40 μL) | 200 μL |
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| TBL1XR1-MCF2L2-20-REGO | 20 (40 μL) | 200 μL |
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| TBL1XR1-MCF2L2-20-REGR | 20 (40 μL) | 200 μL |
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| TBL1XR1-MCF2L2-20-REAQ | 20 (40 μL) | 200 μL |
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| TBL1XR1-MCF2L2-20-ORRE | 20 (40 μL) | 200 μL |
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| TBL1XR1-MCF2L2-20-OROR | 20 (40 μL) | 200 μL |
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| TBL1XR1-MCF2L2-20-ORGO | 20 (40 μL) | 200 μL |
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| TBL1XR1-MCF2L2-20-ORAQ | 20 (40 μL) | 200 μL |
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| TBL1XR1-MCF2L2-20-GORE | 20 (40 μL) | 200 μL |
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| TBL1XR1-MCF2L2-20-GOOR | 20 (40 μL) | 200 μL |
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| TBL1XR1-MCF2L2-20-GOGO | 20 (40 μL) | 200 μL |
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| TBL1XR1-MCF2L2-20-GOGR | 20 (40 μL) | 200 μL |
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| TBL1XR1-MCF2L2-20-GOAQ | 20 (40 μL) | 200 μL |
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| TBL1XR1-MCF2L2-20-GRRE | 20 (40 μL) | 200 μL |
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| TBL1XR1-MCF2L2-20-GROR | 20 (40 μL) | 200 μL |
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| TBL1XR1-MCF2L2-20-GRGO | 20 (40 μL) | 200 μL |
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| TBL1XR1-MCF2L2-20-GRGR | 20 (40 μL) | 200 μL |
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| TBL1XR1-MCF2L2-20-GRAQ | 20 (40 μL) | 200 μL |
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| TBL1XR1-MCF2L2-20-AQRE | 20 (40 μL) | 200 μL |
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| TBL1XR1-MCF2L2-20-AQOR | 20 (40 μL) | 200 μL |
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| TBL1XR1-MCF2L2-20-AQGO | 20 (40 μL) | 200 μL |
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| TBL1XR1-MCF2L2-20-AQGR | 20 (40 μL) | 200 μL |
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| TBL1XR1-MCF2L2-20-AQAQ | 20 (40 μL) | 200 μL |
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MCF2L2 Gene Summary
The MCF.2 Cell Line Derived Transforming Sequence-like 2 (MCF2L2) gene is located on chr3 :182895830-183145855 at 3q27.1.
Gene Name: MCF.2 Cell Line Derived Transforming Sequence-like 2
Chromosome: CHR3: 182895830 -183145855
Locus: 3q27.1
TBL1XR1 Gene Summary
This gene is a member of the WD40 repeat-containing gene family and shares sequence similarity with transducin (beta)-like 1X-linked (TBL1X). The protein encoded by this gene is thought to be a component of both nuclear receptor corepressor (N-CoR) and histone deacetylase 3 (HDAC 3) complexes, and is required for transcriptional activation by a variety of transcription factors. Mutations in these gene have been associated with some autism spectrum disorders, and one finding suggests that haploinsufficiency of this gene may be a cause of intellectual disability with dysmorphism. Mutations in this gene as well as recurrent translocations involving this gene have also been observed in some tumors. [provided by RefSeq, Mar 2016]
Gene Name: Transducin Beta Like 1 X-linked Receptor 1
Chromosome: CHR3: 176738541 -176915048
Locus: 3q26.32
Gene Diseases
The TBL1XR1 MCF2L2 Fusion has been associated with the following diseases:
| Disease Name |
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| Esophageal Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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