TBL1XR1-ADAM33 Fusion FISH Probe
The TBL1XR1-ADAM33 Fusion FISH Probe is used to confirm a fusion of the TBL1XR1 and ADAM33 genes. The fusion of the TBL1XR1 and ADAM33 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TBL1XR1-ADAM33-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TBL1XR1-ADAM33-20-RERE | 20 (40 μL) | 200 μL |
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| TBL1XR1-ADAM33-20-REOR | 20 (40 μL) | 200 μL |
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| TBL1XR1-ADAM33-20-REGO | 20 (40 μL) | 200 μL |
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| TBL1XR1-ADAM33-20-REGR | 20 (40 μL) | 200 μL |
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| TBL1XR1-ADAM33-20-REAQ | 20 (40 μL) | 200 μL |
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| TBL1XR1-ADAM33-20-ORRE | 20 (40 μL) | 200 μL |
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| TBL1XR1-ADAM33-20-OROR | 20 (40 μL) | 200 μL |
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| TBL1XR1-ADAM33-20-ORGO | 20 (40 μL) | 200 μL |
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| TBL1XR1-ADAM33-20-ORAQ | 20 (40 μL) | 200 μL |
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| TBL1XR1-ADAM33-20-GORE | 20 (40 μL) | 200 μL |
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| TBL1XR1-ADAM33-20-GOOR | 20 (40 μL) | 200 μL |
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| TBL1XR1-ADAM33-20-GOGO | 20 (40 μL) | 200 μL |
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| TBL1XR1-ADAM33-20-GOGR | 20 (40 μL) | 200 μL |
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| TBL1XR1-ADAM33-20-GOAQ | 20 (40 μL) | 200 μL |
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| TBL1XR1-ADAM33-20-GRRE | 20 (40 μL) | 200 μL |
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| TBL1XR1-ADAM33-20-GROR | 20 (40 μL) | 200 μL |
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| TBL1XR1-ADAM33-20-GRGO | 20 (40 μL) | 200 μL |
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| TBL1XR1-ADAM33-20-GRGR | 20 (40 μL) | 200 μL |
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| TBL1XR1-ADAM33-20-GRAQ | 20 (40 μL) | 200 μL |
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| TBL1XR1-ADAM33-20-AQRE | 20 (40 μL) | 200 μL |
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| TBL1XR1-ADAM33-20-AQOR | 20 (40 μL) | 200 μL |
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| TBL1XR1-ADAM33-20-AQGO | 20 (40 μL) | 200 μL |
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| TBL1XR1-ADAM33-20-AQGR | 20 (40 μL) | 200 μL |
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| TBL1XR1-ADAM33-20-AQAQ | 20 (40 μL) | 200 μL |
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TBL1XR1 Gene Summary
This gene is a member of the WD40 repeat-containing gene family and shares sequence similarity with transducin (beta)-like 1X-linked (TBL1X). The protein encoded by this gene is thought to be a component of both nuclear receptor corepressor (N-CoR) and histone deacetylase 3 (HDAC 3) complexes, and is required for transcriptional activation by a variety of transcription factors. Mutations in these gene have been associated with some autism spectrum disorders, and one finding suggests that haploinsufficiency of this gene may be a cause of intellectual disability with dysmorphism. Mutations in this gene as well as recurrent translocations involving this gene have also been observed in some tumors. [provided by RefSeq, Mar 2016]
Gene Name: Transducin Beta Like 1 X-linked Receptor 1
Chromosome: CHR3: 176738541 -176915048
Locus: 3q26.32
ADAM33 Gene Summary
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This protein is a type I transmembrane protein implicated in asthma and bronchial hyperresponsiveness. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2013]
Gene Name: ADAM Metallopeptidase Domain 33
Chromosome: CHR20: 3648619 -3662738
Locus: 20p13
Gene Diseases
The TBL1XR1 ADAM33 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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