TBCK-WDHD1 Fusion FISH Probe
The TBCK-WDHD1 Fusion FISH Probe is used to confirm a fusion of the TBCK and WDHD1 genes. The fusion of the TBCK and WDHD1 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TBCK-WDHD1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TBCK-WDHD1-20-RERE | 20 (40 μL) | 200 μL |
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| TBCK-WDHD1-20-REOR | 20 (40 μL) | 200 μL |
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| TBCK-WDHD1-20-REGO | 20 (40 μL) | 200 μL |
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| TBCK-WDHD1-20-REGR | 20 (40 μL) | 200 μL |
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| TBCK-WDHD1-20-REAQ | 20 (40 μL) | 200 μL |
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| TBCK-WDHD1-20-ORRE | 20 (40 μL) | 200 μL |
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| TBCK-WDHD1-20-OROR | 20 (40 μL) | 200 μL |
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| TBCK-WDHD1-20-ORGO | 20 (40 μL) | 200 μL |
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| TBCK-WDHD1-20-ORAQ | 20 (40 μL) | 200 μL |
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| TBCK-WDHD1-20-GORE | 20 (40 μL) | 200 μL |
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| TBCK-WDHD1-20-GOOR | 20 (40 μL) | 200 μL |
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| TBCK-WDHD1-20-GOGO | 20 (40 μL) | 200 μL |
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| TBCK-WDHD1-20-GOGR | 20 (40 μL) | 200 μL |
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| TBCK-WDHD1-20-GOAQ | 20 (40 μL) | 200 μL |
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| TBCK-WDHD1-20-GRRE | 20 (40 μL) | 200 μL |
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| TBCK-WDHD1-20-GROR | 20 (40 μL) | 200 μL |
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| TBCK-WDHD1-20-GRGO | 20 (40 μL) | 200 μL |
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| TBCK-WDHD1-20-GRGR | 20 (40 μL) | 200 μL |
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| TBCK-WDHD1-20-GRAQ | 20 (40 μL) | 200 μL |
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| TBCK-WDHD1-20-AQRE | 20 (40 μL) | 200 μL |
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| TBCK-WDHD1-20-AQOR | 20 (40 μL) | 200 μL |
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| TBCK-WDHD1-20-AQGO | 20 (40 μL) | 200 μL |
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| TBCK-WDHD1-20-AQGR | 20 (40 μL) | 200 μL |
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| TBCK-WDHD1-20-AQAQ | 20 (40 μL) | 200 μL |
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WDHD1 Gene Summary
The protein encoded by this gene contains multiple N-terminal WD40 domains and a C-terminal high mobility group (HMG) box. WD40 domains are found in a variety of eukaryotic proteins and may function as adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly. HMG boxes are found in many eukaryotic proteins involved in chromatin assembly, transcription and replication. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Name: WD Repeat And HMG-box DNA Binding Protein 1
Chromosome: CHR14: 55405655 -55493819
Locus: 14q22.2-q22.3
TBCK Gene Summary
This gene encodes a protein that contains a protein kinase domain, a Rhodanase-like domain and the Tre-2/Bub2/Cdc16 (TBC) domain. The encoded protein is thought to play a role in actin organization, cell growth and cell proliferation by regulating the mammalian target of the rapamycin (mTOR) signaling pathway. This protein may also be involved in the transcriptional regulation of the components of the mTOR complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]
Gene Name: TBC1 Domain Containing Kinase
Chromosome: CHR4: 106967232 -107237861
Locus: 4q24
Gene Diseases
The TBCK WDHD1 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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