TBCE-SIPA1L2 Fusion FISH Probe
The TBCE-SIPA1L2 Fusion FISH Probe is used to confirm a fusion of the TBCE and SIPA1L2 genes. The fusion of the TBCE and SIPA1L2 genes has been associated with Mesothelioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TBCE-SIPA1L2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TBCE-SIPA1L2-20-RERE | 20 (40 μL) | 200 μL |
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| TBCE-SIPA1L2-20-REOR | 20 (40 μL) | 200 μL |
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| TBCE-SIPA1L2-20-REGO | 20 (40 μL) | 200 μL |
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| TBCE-SIPA1L2-20-REGR | 20 (40 μL) | 200 μL |
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| TBCE-SIPA1L2-20-REAQ | 20 (40 μL) | 200 μL |
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| TBCE-SIPA1L2-20-ORRE | 20 (40 μL) | 200 μL |
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| TBCE-SIPA1L2-20-OROR | 20 (40 μL) | 200 μL |
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| TBCE-SIPA1L2-20-ORGO | 20 (40 μL) | 200 μL |
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| TBCE-SIPA1L2-20-ORAQ | 20 (40 μL) | 200 μL |
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| TBCE-SIPA1L2-20-GORE | 20 (40 μL) | 200 μL |
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| TBCE-SIPA1L2-20-GOOR | 20 (40 μL) | 200 μL |
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| TBCE-SIPA1L2-20-GOGO | 20 (40 μL) | 200 μL |
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| TBCE-SIPA1L2-20-GOGR | 20 (40 μL) | 200 μL |
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| TBCE-SIPA1L2-20-GOAQ | 20 (40 μL) | 200 μL |
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| TBCE-SIPA1L2-20-GRRE | 20 (40 μL) | 200 μL |
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| TBCE-SIPA1L2-20-GROR | 20 (40 μL) | 200 μL |
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| TBCE-SIPA1L2-20-GRGO | 20 (40 μL) | 200 μL |
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| TBCE-SIPA1L2-20-GRGR | 20 (40 μL) | 200 μL |
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| TBCE-SIPA1L2-20-GRAQ | 20 (40 μL) | 200 μL |
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| TBCE-SIPA1L2-20-AQRE | 20 (40 μL) | 200 μL |
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| TBCE-SIPA1L2-20-AQOR | 20 (40 μL) | 200 μL |
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| TBCE-SIPA1L2-20-AQGO | 20 (40 μL) | 200 μL |
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| TBCE-SIPA1L2-20-AQGR | 20 (40 μL) | 200 μL |
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| TBCE-SIPA1L2-20-AQAQ | 20 (40 μL) | 200 μL |
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TBCE Gene Summary
Cofactor E is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Tubulin Folding Cofactor E
Chromosome: CHR1: 235530727 -235612280
Locus: 1q42.3
SIPA1L2 Gene Summary
This gene encodes a member of the signal-induced proliferation-associated 1 like family. Members of this family contain a GTPase activating domain, a PDZ domain and a C-terminal coiled-coil domain with a leucine zipper. A similar protein in rat acts as a GTPases for the small GTPase Rap. [provided by RefSeq, Sep 2015]
Gene Name: Signal Induced Proliferation Associated 1 Like 2
Chromosome: CHR1: 232533711 -232651243
Locus: 1q42.2
Gene Diseases
The TBCE SIPA1L2 Fusion has been associated with the following diseases:
| Disease Name |
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| Mesothelioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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