TBCE-MAPRE2 Fusion FISH Probe
The TBCE-MAPRE2 Fusion FISH Probe is used to confirm a fusion of the TBCE and MAPRE2 genes. The fusion of the TBCE and MAPRE2 genes has been associated with Thymoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TBCE-MAPRE2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TBCE-MAPRE2-20-RERE | 20 (40 μL) | 200 μL |
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| TBCE-MAPRE2-20-REOR | 20 (40 μL) | 200 μL |
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| TBCE-MAPRE2-20-REGO | 20 (40 μL) | 200 μL |
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| TBCE-MAPRE2-20-REGR | 20 (40 μL) | 200 μL |
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| TBCE-MAPRE2-20-REAQ | 20 (40 μL) | 200 μL |
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| TBCE-MAPRE2-20-ORRE | 20 (40 μL) | 200 μL |
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| TBCE-MAPRE2-20-OROR | 20 (40 μL) | 200 μL |
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| TBCE-MAPRE2-20-ORGO | 20 (40 μL) | 200 μL |
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| TBCE-MAPRE2-20-ORAQ | 20 (40 μL) | 200 μL |
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| TBCE-MAPRE2-20-GORE | 20 (40 μL) | 200 μL |
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| TBCE-MAPRE2-20-GOOR | 20 (40 μL) | 200 μL |
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| TBCE-MAPRE2-20-GOGO | 20 (40 μL) | 200 μL |
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| TBCE-MAPRE2-20-GOGR | 20 (40 μL) | 200 μL |
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| TBCE-MAPRE2-20-GOAQ | 20 (40 μL) | 200 μL |
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| TBCE-MAPRE2-20-GRRE | 20 (40 μL) | 200 μL |
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| TBCE-MAPRE2-20-GROR | 20 (40 μL) | 200 μL |
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| TBCE-MAPRE2-20-GRGO | 20 (40 μL) | 200 μL |
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| TBCE-MAPRE2-20-GRGR | 20 (40 μL) | 200 μL |
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| TBCE-MAPRE2-20-GRAQ | 20 (40 μL) | 200 μL |
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| TBCE-MAPRE2-20-AQRE | 20 (40 μL) | 200 μL |
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| TBCE-MAPRE2-20-AQOR | 20 (40 μL) | 200 μL |
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| TBCE-MAPRE2-20-AQGO | 20 (40 μL) | 200 μL |
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| TBCE-MAPRE2-20-AQGR | 20 (40 μL) | 200 μL |
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| TBCE-MAPRE2-20-AQAQ | 20 (40 μL) | 200 μL |
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TBCE Gene Summary
Cofactor E is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Tubulin Folding Cofactor E
Chromosome: CHR1: 235530727 -235612280
Locus: 1q42.3
MAPRE2 Gene Summary
The protein encoded by this gene shares significant homology to the adenomatous polyposis coli (APC) protein-binding EB1 gene family. This protein is a microtubule-associated protein that is necessary for spindle symmetry during mitosis. It is thought to play a role in the tumorigenesis of colorectal cancers and the proliferative control of normal cells. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012]
Gene Name: Microtubule Associated Protein RP/EB Family Member 2
Chromosome: CHR18: 32556891 -32722378
Locus: 18q12.1-q12.2
Gene Diseases
The TBCE MAPRE2 Fusion has been associated with the following diseases:
| Disease Name |
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| Thymoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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