TBCE-GGPS1 Fusion FISH Probe
The TBCE-GGPS1 Fusion FISH Probe is used to confirm a fusion of the TBCE and GGPS1 genes. The fusion of the TBCE and GGPS1 genes has been associated with Lung Squamous Cell Carcinoma, and Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TBCE-GGPS1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TBCE-GGPS1-20-RERE | 20 (40 μL) | 200 μL |
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| TBCE-GGPS1-20-REOR | 20 (40 μL) | 200 μL |
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| TBCE-GGPS1-20-REGO | 20 (40 μL) | 200 μL |
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| TBCE-GGPS1-20-REGR | 20 (40 μL) | 200 μL |
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| TBCE-GGPS1-20-REAQ | 20 (40 μL) | 200 μL |
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| TBCE-GGPS1-20-ORRE | 20 (40 μL) | 200 μL |
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| TBCE-GGPS1-20-OROR | 20 (40 μL) | 200 μL |
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| TBCE-GGPS1-20-ORGO | 20 (40 μL) | 200 μL |
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| TBCE-GGPS1-20-ORAQ | 20 (40 μL) | 200 μL |
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| TBCE-GGPS1-20-GORE | 20 (40 μL) | 200 μL |
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| TBCE-GGPS1-20-GOOR | 20 (40 μL) | 200 μL |
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| TBCE-GGPS1-20-GOGO | 20 (40 μL) | 200 μL |
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| TBCE-GGPS1-20-GOGR | 20 (40 μL) | 200 μL |
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| TBCE-GGPS1-20-GOAQ | 20 (40 μL) | 200 μL |
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| TBCE-GGPS1-20-GRRE | 20 (40 μL) | 200 μL |
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| TBCE-GGPS1-20-GROR | 20 (40 μL) | 200 μL |
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| TBCE-GGPS1-20-GRGO | 20 (40 μL) | 200 μL |
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| TBCE-GGPS1-20-GRGR | 20 (40 μL) | 200 μL |
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| TBCE-GGPS1-20-GRAQ | 20 (40 μL) | 200 μL |
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| TBCE-GGPS1-20-AQRE | 20 (40 μL) | 200 μL |
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| TBCE-GGPS1-20-AQOR | 20 (40 μL) | 200 μL |
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| TBCE-GGPS1-20-AQGO | 20 (40 μL) | 200 μL |
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| TBCE-GGPS1-20-AQGR | 20 (40 μL) | 200 μL |
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| TBCE-GGPS1-20-AQAQ | 20 (40 μL) | 200 μL |
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TBCE Gene Summary
Cofactor E is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Tubulin Folding Cofactor E
Chromosome: CHR1: 235530727 -235612280
Locus: 1q42.3
GGPS1 Gene Summary
This gene is a member of the prenyltransferase family and encodes a protein with geranylgeranyl diphosphate (GGPP) synthase activity. The enzyme catalyzes the synthesis of GGPP from farnesyl diphosphate and isopentenyl diphosphate. GGPP is an important molecule responsible for the C20-prenylation of proteins and for the regulation of a nuclear hormone receptor. Alternate transcriptional splice variants, both protein-coding and non-protein-coding, have been found for this gene. [provided by RefSeq, Sep 2010]
Gene Name: Geranylgeranyl Diphosphate Synthase 1
Chromosome: CHR1: 235491752 -235507844
Locus: 1q42.3
Gene Diseases
The TBCE GGPS1 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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