TBCD-ASPSCR1 Fusion FISH Probe
The TBCD-ASPSCR1 Fusion FISH Probe is used to confirm a fusion of the TBCD and ASPSCR1 genes. The fusion of the TBCD and ASPSCR1 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TBCD-ASPSCR1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| TBCD-ASPSCR1-20-RERE | 20 (40 μL) | 200 μL |
|
|
| TBCD-ASPSCR1-20-REOR | 20 (40 μL) | 200 μL |
|
|
| TBCD-ASPSCR1-20-REGO | 20 (40 μL) | 200 μL |
|
|
| TBCD-ASPSCR1-20-REGR | 20 (40 μL) | 200 μL |
|
|
| TBCD-ASPSCR1-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| TBCD-ASPSCR1-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| TBCD-ASPSCR1-20-OROR | 20 (40 μL) | 200 μL |
|
|
| TBCD-ASPSCR1-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| TBCD-ASPSCR1-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| TBCD-ASPSCR1-20-GORE | 20 (40 μL) | 200 μL |
|
|
| TBCD-ASPSCR1-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| TBCD-ASPSCR1-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| TBCD-ASPSCR1-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| TBCD-ASPSCR1-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| TBCD-ASPSCR1-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| TBCD-ASPSCR1-20-GROR | 20 (40 μL) | 200 μL |
|
|
| TBCD-ASPSCR1-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| TBCD-ASPSCR1-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| TBCD-ASPSCR1-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| TBCD-ASPSCR1-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| TBCD-ASPSCR1-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| TBCD-ASPSCR1-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| TBCD-ASPSCR1-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| TBCD-ASPSCR1-20-AQAQ | 20 (40 μL) | 200 μL |
|
TBCD Gene Summary
Cofactor D is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state. [provided by RefSeq, Jul 2008]
Gene Name: Tubulin Folding Cofactor D
Chromosome: CHR17: 80709939 -80901062
Locus: 17q25.3
ASPSCR1 Gene Summary
The protein encoded by this gene contains a UBX domain and interacts with glucose transporter type 4 (GLUT4). This protein is a tether, which sequesters the GLUT4 in intracellular vesicles in muscle and fat cells in the absence of insulin, and redistributes the GLUT4 to the plasma membrane within minutes of insulin stimulation. Translocation t(X;17)(p11;q25) of this gene with transcription factor TFE3 gene results in a ASPSCR1-TFE3 fusion protein in alveolar soft part sarcoma and in renal cell carcinomas. Multiple alternatively spliced transcript variants have been found. [provided by RefSeq, Oct 2011]
Gene Name: ASPSCR1, UBX Domain Containing Tether For SLC2A4
Chromosome: CHR17: 79935425 -79975282
Locus: 17q25.3
Gene Diseases
The TBCD ASPSCR1 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|