TBC1D2B-CIB2 Fusion FISH Probe
The TBC1D2B-CIB2 Fusion FISH Probe is used to confirm a fusion of the TBC1D2B and CIB2 genes. The fusion of the TBC1D2B and CIB2 genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TBC1D2B-CIB2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TBC1D2B-CIB2-20-RERE | 20 (40 μL) | 200 μL |
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| TBC1D2B-CIB2-20-REOR | 20 (40 μL) | 200 μL |
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| TBC1D2B-CIB2-20-REGO | 20 (40 μL) | 200 μL |
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| TBC1D2B-CIB2-20-REGR | 20 (40 μL) | 200 μL |
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| TBC1D2B-CIB2-20-REAQ | 20 (40 μL) | 200 μL |
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| TBC1D2B-CIB2-20-ORRE | 20 (40 μL) | 200 μL |
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| TBC1D2B-CIB2-20-OROR | 20 (40 μL) | 200 μL |
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| TBC1D2B-CIB2-20-ORGO | 20 (40 μL) | 200 μL |
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| TBC1D2B-CIB2-20-ORAQ | 20 (40 μL) | 200 μL |
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| TBC1D2B-CIB2-20-GORE | 20 (40 μL) | 200 μL |
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| TBC1D2B-CIB2-20-GOOR | 20 (40 μL) | 200 μL |
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| TBC1D2B-CIB2-20-GOGO | 20 (40 μL) | 200 μL |
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| TBC1D2B-CIB2-20-GOGR | 20 (40 μL) | 200 μL |
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| TBC1D2B-CIB2-20-GOAQ | 20 (40 μL) | 200 μL |
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| TBC1D2B-CIB2-20-GRRE | 20 (40 μL) | 200 μL |
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| TBC1D2B-CIB2-20-GROR | 20 (40 μL) | 200 μL |
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| TBC1D2B-CIB2-20-GRGO | 20 (40 μL) | 200 μL |
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| TBC1D2B-CIB2-20-GRGR | 20 (40 μL) | 200 μL |
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| TBC1D2B-CIB2-20-GRAQ | 20 (40 μL) | 200 μL |
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| TBC1D2B-CIB2-20-AQRE | 20 (40 μL) | 200 μL |
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| TBC1D2B-CIB2-20-AQOR | 20 (40 μL) | 200 μL |
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| TBC1D2B-CIB2-20-AQGO | 20 (40 μL) | 200 μL |
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| TBC1D2B-CIB2-20-AQGR | 20 (40 μL) | 200 μL |
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| TBC1D2B-CIB2-20-AQAQ | 20 (40 μL) | 200 μL |
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CIB2 Gene Summary
The protein encoded by this gene is similar to that of KIP/CIB, calcineurin B, and calmodulin. The encoded protein is a calcium-binding regulatory protein that interacts with DNA-dependent protein kinase catalytic subunits (DNA-PKcs), and it is involved in photoreceptor cell maintenance. Mutations in this gene cause deafness, autosomal recessive, 48 (DFNB48), and also Usher syndrome 1J (USH1J). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Gene Name: Calcium And Integrin Binding Family Member 2
Chromosome: CHR15: 78396990 -78423878
Locus: 15q25.1
TBC1D2B Gene Summary
The TBC1 Domain Family Member 2B (TBC1D2B) gene is located on chr15 :78287326-78369994 at 15q24.3-q25.1.
Gene Name: TBC1 Domain Family Member 2B
Chromosome: CHR15: 78287326 -78369994
Locus: 15q24.3-q25.1
Gene Diseases
The TBC1D2B CIB2 Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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