TBC1D22A-GRAP2 Fusion FISH Probe
The TBC1D22A-GRAP2 Fusion FISH Probe is used to confirm a fusion of the TBC1D22A and GRAP2 genes. The fusion of the TBC1D22A and GRAP2 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TBC1D22A-GRAP2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TBC1D22A-GRAP2-20-RERE | 20 (40 μL) | 200 μL |
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| TBC1D22A-GRAP2-20-REOR | 20 (40 μL) | 200 μL |
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| TBC1D22A-GRAP2-20-REGO | 20 (40 μL) | 200 μL |
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| TBC1D22A-GRAP2-20-REGR | 20 (40 μL) | 200 μL |
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| TBC1D22A-GRAP2-20-REAQ | 20 (40 μL) | 200 μL |
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| TBC1D22A-GRAP2-20-ORRE | 20 (40 μL) | 200 μL |
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| TBC1D22A-GRAP2-20-OROR | 20 (40 μL) | 200 μL |
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| TBC1D22A-GRAP2-20-ORGO | 20 (40 μL) | 200 μL |
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| TBC1D22A-GRAP2-20-ORAQ | 20 (40 μL) | 200 μL |
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| TBC1D22A-GRAP2-20-GORE | 20 (40 μL) | 200 μL |
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| TBC1D22A-GRAP2-20-GOOR | 20 (40 μL) | 200 μL |
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| TBC1D22A-GRAP2-20-GOGO | 20 (40 μL) | 200 μL |
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| TBC1D22A-GRAP2-20-GOGR | 20 (40 μL) | 200 μL |
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| TBC1D22A-GRAP2-20-GOAQ | 20 (40 μL) | 200 μL |
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| TBC1D22A-GRAP2-20-GRRE | 20 (40 μL) | 200 μL |
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| TBC1D22A-GRAP2-20-GROR | 20 (40 μL) | 200 μL |
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| TBC1D22A-GRAP2-20-GRGO | 20 (40 μL) | 200 μL |
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| TBC1D22A-GRAP2-20-GRGR | 20 (40 μL) | 200 μL |
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| TBC1D22A-GRAP2-20-GRAQ | 20 (40 μL) | 200 μL |
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| TBC1D22A-GRAP2-20-AQRE | 20 (40 μL) | 200 μL |
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| TBC1D22A-GRAP2-20-AQOR | 20 (40 μL) | 200 μL |
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| TBC1D22A-GRAP2-20-AQGO | 20 (40 μL) | 200 μL |
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| TBC1D22A-GRAP2-20-AQGR | 20 (40 μL) | 200 μL |
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| TBC1D22A-GRAP2-20-AQAQ | 20 (40 μL) | 200 μL |
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GRAP2 Gene Summary
This gene encodes a member of the GRB2/Sem5/Drk family. This member is an adaptor-like protein involved in leukocyte-specific protein-tyrosine kinase signaling. Like its related family member, GRB2-related adaptor protein (GRAP), this protein contains an SH2 domain flanked by two SH3 domains. This protein interacts with other proteins, such as GRB2-associated binding protein 1 (GAB1) and the SLP-76 leukocyte protein (LCP2), through its SH3 domains. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Apr 2014]
Gene Name: GRB2-related Adaptor Protein 2
Chromosome: CHR22: 40297085 -40367384
Locus: 22q13.1
TBC1D22A Gene Summary
The TBC1 Domain Family Member 22A (TBC1D22A) gene is located on chr22 :47158517-47571342 at 22q13.31.
Gene Name: TBC1 Domain Family Member 22A
Chromosome: CHR22: 47158517 -47571342
Locus: 22q13.31
Gene Diseases
The TBC1D22A GRAP2 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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