TBC1D22A-GCAT Fusion FISH Probe
The TBC1D22A-GCAT Fusion FISH Probe is used to confirm a fusion of the TBC1D22A and GCAT genes. The fusion of the TBC1D22A and GCAT genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TBC1D22A-GCAT-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TBC1D22A-GCAT-20-RERE | 20 (40 μL) | 200 μL |
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| TBC1D22A-GCAT-20-REOR | 20 (40 μL) | 200 μL |
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| TBC1D22A-GCAT-20-REGO | 20 (40 μL) | 200 μL |
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| TBC1D22A-GCAT-20-REGR | 20 (40 μL) | 200 μL |
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| TBC1D22A-GCAT-20-REAQ | 20 (40 μL) | 200 μL |
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| TBC1D22A-GCAT-20-ORRE | 20 (40 μL) | 200 μL |
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| TBC1D22A-GCAT-20-OROR | 20 (40 μL) | 200 μL |
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| TBC1D22A-GCAT-20-ORGO | 20 (40 μL) | 200 μL |
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| TBC1D22A-GCAT-20-ORAQ | 20 (40 μL) | 200 μL |
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| TBC1D22A-GCAT-20-GORE | 20 (40 μL) | 200 μL |
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| TBC1D22A-GCAT-20-GOOR | 20 (40 μL) | 200 μL |
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| TBC1D22A-GCAT-20-GOGO | 20 (40 μL) | 200 μL |
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| TBC1D22A-GCAT-20-GOGR | 20 (40 μL) | 200 μL |
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| TBC1D22A-GCAT-20-GOAQ | 20 (40 μL) | 200 μL |
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| TBC1D22A-GCAT-20-GRRE | 20 (40 μL) | 200 μL |
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| TBC1D22A-GCAT-20-GROR | 20 (40 μL) | 200 μL |
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| TBC1D22A-GCAT-20-GRGO | 20 (40 μL) | 200 μL |
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| TBC1D22A-GCAT-20-GRGR | 20 (40 μL) | 200 μL |
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| TBC1D22A-GCAT-20-GRAQ | 20 (40 μL) | 200 μL |
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| TBC1D22A-GCAT-20-AQRE | 20 (40 μL) | 200 μL |
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| TBC1D22A-GCAT-20-AQOR | 20 (40 μL) | 200 μL |
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| TBC1D22A-GCAT-20-AQGO | 20 (40 μL) | 200 μL |
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| TBC1D22A-GCAT-20-AQGR | 20 (40 μL) | 200 μL |
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| TBC1D22A-GCAT-20-AQAQ | 20 (40 μL) | 200 μL |
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GCAT Gene Summary
The degradation of L-threonine to glycine consists of a two-step biochemical pathway involving the enzymes L-threonine dehydrogenase and 2-amino-3-ketobutyrate coenzyme A ligase. L-Threonine is first converted into 2-amino-3-ketobutyrate by L-threonine dehydrogenase. This gene encodes the second enzyme in this pathway, which then catalyzes the reaction between 2-amino-3-ketobutyrate and coenzyme A to form glycine and acetyl-CoA. The encoded enzyme is considered a class II pyridoxal-phosphate-dependent aminotransferase. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 14. [provided by RefSeq, Jan 2010]
Gene Name: Glycine C-acetyltransferase
Chromosome: CHR22: 38203911 -38213183
Locus: 22q13.1
TBC1D22A Gene Summary
The TBC1 Domain Family Member 22A (TBC1D22A) gene is located on chr22 :47158517-47571342 at 22q13.31.
Gene Name: TBC1 Domain Family Member 22A
Chromosome: CHR22: 47158517 -47571342
Locus: 22q13.31
Gene Diseases
The TBC1D22A GCAT Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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