TBC1D19-ANAPC4 Fusion FISH Probe
The TBC1D19-ANAPC4 Fusion FISH Probe is used to confirm a fusion of the TBC1D19 and ANAPC4 genes. The fusion of the TBC1D19 and ANAPC4 genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TBC1D19-ANAPC4-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TBC1D19-ANAPC4-20-RERE | 20 (40 μL) | 200 μL |
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| TBC1D19-ANAPC4-20-REOR | 20 (40 μL) | 200 μL |
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| TBC1D19-ANAPC4-20-REGO | 20 (40 μL) | 200 μL |
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| TBC1D19-ANAPC4-20-REGR | 20 (40 μL) | 200 μL |
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| TBC1D19-ANAPC4-20-REAQ | 20 (40 μL) | 200 μL |
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| TBC1D19-ANAPC4-20-ORRE | 20 (40 μL) | 200 μL |
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| TBC1D19-ANAPC4-20-OROR | 20 (40 μL) | 200 μL |
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| TBC1D19-ANAPC4-20-ORGO | 20 (40 μL) | 200 μL |
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| TBC1D19-ANAPC4-20-ORAQ | 20 (40 μL) | 200 μL |
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| TBC1D19-ANAPC4-20-GORE | 20 (40 μL) | 200 μL |
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| TBC1D19-ANAPC4-20-GOOR | 20 (40 μL) | 200 μL |
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| TBC1D19-ANAPC4-20-GOGO | 20 (40 μL) | 200 μL |
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| TBC1D19-ANAPC4-20-GOGR | 20 (40 μL) | 200 μL |
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| TBC1D19-ANAPC4-20-GOAQ | 20 (40 μL) | 200 μL |
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| TBC1D19-ANAPC4-20-GRRE | 20 (40 μL) | 200 μL |
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| TBC1D19-ANAPC4-20-GROR | 20 (40 μL) | 200 μL |
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| TBC1D19-ANAPC4-20-GRGO | 20 (40 μL) | 200 μL |
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| TBC1D19-ANAPC4-20-GRGR | 20 (40 μL) | 200 μL |
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| TBC1D19-ANAPC4-20-GRAQ | 20 (40 μL) | 200 μL |
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| TBC1D19-ANAPC4-20-AQRE | 20 (40 μL) | 200 μL |
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| TBC1D19-ANAPC4-20-AQOR | 20 (40 μL) | 200 μL |
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| TBC1D19-ANAPC4-20-AQGO | 20 (40 μL) | 200 μL |
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| TBC1D19-ANAPC4-20-AQGR | 20 (40 μL) | 200 μL |
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| TBC1D19-ANAPC4-20-AQAQ | 20 (40 μL) | 200 μL |
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ANAPC4 Gene Summary
A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eight subunits. The composition of the APC is highly conserved in organisms from yeast to humans. The exact function of this gene product is not known. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]
Gene Name: Anaphase Promoting Complex Subunit 4
Chromosome: CHR4: 25378847 -25420120
Locus: 4p15.2
TBC1D19 Gene Summary
The TBC1 Domain Family Member 19 (TBC1D19) gene is located on chr4 :26585545-26756918 at 4p15.2.
Gene Name: TBC1 Domain Family Member 19
Chromosome: CHR4: 26585545 -26756918
Locus: 4p15.2
Gene Diseases
The TBC1D19 ANAPC4 Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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