TBC1D12-EXOC6 Fusion FISH Probe
The TBC1D12-EXOC6 Fusion FISH Probe is used to confirm a fusion of the TBC1D12 and EXOC6 genes. The fusion of the TBC1D12 and EXOC6 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TBC1D12-EXOC6-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| TBC1D12-EXOC6-20-RERE | 20 (40 μL) | 200 μL |
|
|
| TBC1D12-EXOC6-20-REOR | 20 (40 μL) | 200 μL |
|
|
| TBC1D12-EXOC6-20-REGO | 20 (40 μL) | 200 μL |
|
|
| TBC1D12-EXOC6-20-REGR | 20 (40 μL) | 200 μL |
|
|
| TBC1D12-EXOC6-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| TBC1D12-EXOC6-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| TBC1D12-EXOC6-20-OROR | 20 (40 μL) | 200 μL |
|
|
| TBC1D12-EXOC6-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| TBC1D12-EXOC6-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| TBC1D12-EXOC6-20-GORE | 20 (40 μL) | 200 μL |
|
|
| TBC1D12-EXOC6-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| TBC1D12-EXOC6-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| TBC1D12-EXOC6-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| TBC1D12-EXOC6-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| TBC1D12-EXOC6-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| TBC1D12-EXOC6-20-GROR | 20 (40 μL) | 200 μL |
|
|
| TBC1D12-EXOC6-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| TBC1D12-EXOC6-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| TBC1D12-EXOC6-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| TBC1D12-EXOC6-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| TBC1D12-EXOC6-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| TBC1D12-EXOC6-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| TBC1D12-EXOC6-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| TBC1D12-EXOC6-20-AQAQ | 20 (40 μL) | 200 μL |
|
TBC1D12 Gene Summary
The TBC1 Domain Family Member 12 (TBC1D12) gene is located on chr10 :96162185-96296089 at 10q23.33.
Gene Name: TBC1 Domain Family Member 12
Chromosome: CHR10: 96162185 -96296089
Locus: 10q23.33
EXOC6 Gene Summary
The protein encoded by this gene is highly similar to the Saccharomyces cerevisiae SEC15 gene product, which is essential for vesicular traffic from the Golgi apparatus to the cell surface in yeast. It is one of the components of a multiprotein complex required for exocytosis. The 5' portion of this gene and two neighboring cytochrome p450 genes are included in a deletion that results in an autosomal-dominant form of nonsyndromic optic nerve aplasia (ONA). Alternative splicing and the use of alternative promoters results in multiple transcript variants. A paralogous gene encoding a similar protein is present on chromosome 2. [provided by RefSeq, Jan 2016]
Gene Name: Exocyst Complex Component 6
Chromosome: CHR10: 94594469 -94819251
Locus: 10q23.33
Gene Diseases
The TBC1D12 EXOC6 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|