TBC1D1-RAB28 Fusion FISH Probe
The TBC1D1-RAB28 Fusion FISH Probe is used to confirm a fusion of the TBC1D1 and RAB28 genes. The fusion of the TBC1D1 and RAB28 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TBC1D1-RAB28-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TBC1D1-RAB28-20-RERE | 20 (40 μL) | 200 μL |
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| TBC1D1-RAB28-20-REOR | 20 (40 μL) | 200 μL |
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| TBC1D1-RAB28-20-REGO | 20 (40 μL) | 200 μL |
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| TBC1D1-RAB28-20-REGR | 20 (40 μL) | 200 μL |
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| TBC1D1-RAB28-20-REAQ | 20 (40 μL) | 200 μL |
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| TBC1D1-RAB28-20-ORRE | 20 (40 μL) | 200 μL |
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| TBC1D1-RAB28-20-OROR | 20 (40 μL) | 200 μL |
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| TBC1D1-RAB28-20-ORGO | 20 (40 μL) | 200 μL |
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| TBC1D1-RAB28-20-ORAQ | 20 (40 μL) | 200 μL |
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| TBC1D1-RAB28-20-GORE | 20 (40 μL) | 200 μL |
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| TBC1D1-RAB28-20-GOOR | 20 (40 μL) | 200 μL |
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| TBC1D1-RAB28-20-GOGO | 20 (40 μL) | 200 μL |
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| TBC1D1-RAB28-20-GOGR | 20 (40 μL) | 200 μL |
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| TBC1D1-RAB28-20-GOAQ | 20 (40 μL) | 200 μL |
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| TBC1D1-RAB28-20-GRRE | 20 (40 μL) | 200 μL |
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| TBC1D1-RAB28-20-GROR | 20 (40 μL) | 200 μL |
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| TBC1D1-RAB28-20-GRGO | 20 (40 μL) | 200 μL |
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| TBC1D1-RAB28-20-GRGR | 20 (40 μL) | 200 μL |
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| TBC1D1-RAB28-20-GRAQ | 20 (40 μL) | 200 μL |
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| TBC1D1-RAB28-20-AQRE | 20 (40 μL) | 200 μL |
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| TBC1D1-RAB28-20-AQOR | 20 (40 μL) | 200 μL |
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| TBC1D1-RAB28-20-AQGO | 20 (40 μL) | 200 μL |
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| TBC1D1-RAB28-20-AQGR | 20 (40 μL) | 200 μL |
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| TBC1D1-RAB28-20-AQAQ | 20 (40 μL) | 200 μL |
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RAB28 Gene Summary
This gene encodes a member of the Rab subfamily of Ras-related small GTPases. The encoded protein may be involved in regulating intracellular trafficking. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 9 and X. [provided by RefSeq, Apr 2009]
Gene Name: RAB28, Member RAS Oncogene Family
Chromosome: CHR4: 13369346 -13485989
Locus: 4p15.33
TBC1D1 Gene Summary
TBC1D1 is the founding member of a family of proteins sharing a 180- to 200-amino acid TBC domain presumed to have a role in regulating cell growth and differentiation. These proteins share significant homology with TRE2 (USP6; MIM 604334), yeast Bub2, and CDC16 (MIM 603461) (White et al., 2000 [PubMed 10965142]).[supplied by OMIM, Mar 2008]
Gene Name: TBC1 Domain Family Member 1
Chromosome: CHR4: 37892719 -38140794
Locus: 4p14
Gene Diseases
The TBC1D1 RAB28 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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