TAX1BP1-JAZF1 Fusion FISH Probe
The TAX1BP1-JAZF1 Fusion FISH Probe is used to confirm a fusion of the TAX1BP1 and JAZF1 genes. The fusion of the TAX1BP1 and JAZF1 genes has been associated with Ovarian Serous Cystadenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TAX1BP1-JAZF1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TAX1BP1-JAZF1-20-RERE | 20 (40 μL) | 200 μL |
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| TAX1BP1-JAZF1-20-REOR | 20 (40 μL) | 200 μL |
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| TAX1BP1-JAZF1-20-REGO | 20 (40 μL) | 200 μL |
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| TAX1BP1-JAZF1-20-REGR | 20 (40 μL) | 200 μL |
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| TAX1BP1-JAZF1-20-REAQ | 20 (40 μL) | 200 μL |
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| TAX1BP1-JAZF1-20-ORRE | 20 (40 μL) | 200 μL |
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| TAX1BP1-JAZF1-20-OROR | 20 (40 μL) | 200 μL |
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| TAX1BP1-JAZF1-20-ORGO | 20 (40 μL) | 200 μL |
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| TAX1BP1-JAZF1-20-ORAQ | 20 (40 μL) | 200 μL |
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| TAX1BP1-JAZF1-20-GORE | 20 (40 μL) | 200 μL |
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| TAX1BP1-JAZF1-20-GOOR | 20 (40 μL) | 200 μL |
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| TAX1BP1-JAZF1-20-GOGO | 20 (40 μL) | 200 μL |
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| TAX1BP1-JAZF1-20-GOGR | 20 (40 μL) | 200 μL |
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| TAX1BP1-JAZF1-20-GOAQ | 20 (40 μL) | 200 μL |
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| TAX1BP1-JAZF1-20-GRRE | 20 (40 μL) | 200 μL |
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| TAX1BP1-JAZF1-20-GROR | 20 (40 μL) | 200 μL |
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| TAX1BP1-JAZF1-20-GRGO | 20 (40 μL) | 200 μL |
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| TAX1BP1-JAZF1-20-GRGR | 20 (40 μL) | 200 μL |
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| TAX1BP1-JAZF1-20-GRAQ | 20 (40 μL) | 200 μL |
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| TAX1BP1-JAZF1-20-AQRE | 20 (40 μL) | 200 μL |
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| TAX1BP1-JAZF1-20-AQOR | 20 (40 μL) | 200 μL |
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| TAX1BP1-JAZF1-20-AQGO | 20 (40 μL) | 200 μL |
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| TAX1BP1-JAZF1-20-AQGR | 20 (40 μL) | 200 μL |
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| TAX1BP1-JAZF1-20-AQAQ | 20 (40 μL) | 200 μL |
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TAX1BP1 Gene Summary
This gene encodes a HTLV-1 tax1 binding protein. The encoded protein interacts with TNFAIP3, and inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degradation of this protein by caspase-3-like family proteins is associated with apoptosis induced by TNF. This protein may also have a role in the inhibition of inflammatory signaling pathways. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2011]
Gene Name: Tax1 Binding Protein 1
Chromosome: CHR7: 27778991 -27869386
Locus: 7p15.2
JAZF1 Gene Summary
This gene encodes a nuclear protein with three C2H2-type zinc fingers, and functions as a transcriptional repressor. Chromosomal aberrations involving this gene are associated with endometrial stromal tumors. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized [provided by RefSeq, Jul 2008]
Gene Name: JAZF Zinc Finger 1
Chromosome: CHR7: 27870192 -28220437
Locus: 7p15.2-p15.1
Gene Diseases
The TAX1BP1 JAZF1 Fusion has been associated with the following diseases:
| Disease Name |
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| Ovarian Serous Cystadenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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