TATDN2-FANCD2 Fusion FISH Probe
The TATDN2-FANCD2 Fusion FISH Probe is used to confirm a fusion of the TATDN2 and FANCD2 genes. The fusion of the TATDN2 and FANCD2 genes has been associated with Esophageal Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TATDN2-FANCD2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TATDN2-FANCD2-20-RERE | 20 (40 μL) | 200 μL |
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| TATDN2-FANCD2-20-REOR | 20 (40 μL) | 200 μL |
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| TATDN2-FANCD2-20-REGO | 20 (40 μL) | 200 μL |
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| TATDN2-FANCD2-20-REGR | 20 (40 μL) | 200 μL |
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| TATDN2-FANCD2-20-REAQ | 20 (40 μL) | 200 μL |
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| TATDN2-FANCD2-20-ORRE | 20 (40 μL) | 200 μL |
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| TATDN2-FANCD2-20-OROR | 20 (40 μL) | 200 μL |
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| TATDN2-FANCD2-20-ORGO | 20 (40 μL) | 200 μL |
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| TATDN2-FANCD2-20-ORAQ | 20 (40 μL) | 200 μL |
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| TATDN2-FANCD2-20-GORE | 20 (40 μL) | 200 μL |
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| TATDN2-FANCD2-20-GOOR | 20 (40 μL) | 200 μL |
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| TATDN2-FANCD2-20-GOGO | 20 (40 μL) | 200 μL |
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| TATDN2-FANCD2-20-GOGR | 20 (40 μL) | 200 μL |
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| TATDN2-FANCD2-20-GOAQ | 20 (40 μL) | 200 μL |
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| TATDN2-FANCD2-20-GRRE | 20 (40 μL) | 200 μL |
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| TATDN2-FANCD2-20-GROR | 20 (40 μL) | 200 μL |
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| TATDN2-FANCD2-20-GRGO | 20 (40 μL) | 200 μL |
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| TATDN2-FANCD2-20-GRGR | 20 (40 μL) | 200 μL |
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| TATDN2-FANCD2-20-GRAQ | 20 (40 μL) | 200 μL |
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| TATDN2-FANCD2-20-AQRE | 20 (40 μL) | 200 μL |
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| TATDN2-FANCD2-20-AQOR | 20 (40 μL) | 200 μL |
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| TATDN2-FANCD2-20-AQGO | 20 (40 μL) | 200 μL |
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| TATDN2-FANCD2-20-AQGR | 20 (40 μL) | 200 μL |
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| TATDN2-FANCD2-20-AQAQ | 20 (40 μL) | 200 μL |
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FANCD2 Gene Summary
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group D2. This protein is monoubiquinated in response to DNA damage, resulting in its localization to nuclear foci with other proteins (BRCA1 AND BRCA2) involved in homology-directed DNA repair. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
Gene Name: Fanconi Anemia Complementation Group D2
Chromosome: CHR3: 10068112 -10143614
Locus: 3p25.3
TATDN2 Gene Summary
The TatD DNase Domain Containing 2 (TATDN2) gene is located on chr3 :10290176-10322906 at 3p25.3.
Gene Name: TatD DNase Domain Containing 2
Chromosome: CHR3: 10290176 -10322906
Locus: 3p25.3
Gene Diseases
The TATDN2 FANCD2 Fusion has been associated with the following diseases:
| Disease Name |
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| Esophageal Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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