TARBP1-ARID4B Fusion FISH Probe
The TARBP1-ARID4B Fusion FISH Probe is used to confirm a fusion of the TARBP1 and ARID4B genes. The fusion of the TARBP1 and ARID4B genes has been associated with Pancreatic Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TARBP1-ARID4B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TARBP1-ARID4B-20-RERE | 20 (40 μL) | 200 μL |
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| TARBP1-ARID4B-20-REOR | 20 (40 μL) | 200 μL |
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| TARBP1-ARID4B-20-REGO | 20 (40 μL) | 200 μL |
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| TARBP1-ARID4B-20-REGR | 20 (40 μL) | 200 μL |
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| TARBP1-ARID4B-20-REAQ | 20 (40 μL) | 200 μL |
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| TARBP1-ARID4B-20-ORRE | 20 (40 μL) | 200 μL |
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| TARBP1-ARID4B-20-OROR | 20 (40 μL) | 200 μL |
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| TARBP1-ARID4B-20-ORGO | 20 (40 μL) | 200 μL |
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| TARBP1-ARID4B-20-ORAQ | 20 (40 μL) | 200 μL |
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| TARBP1-ARID4B-20-GORE | 20 (40 μL) | 200 μL |
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| TARBP1-ARID4B-20-GOOR | 20 (40 μL) | 200 μL |
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| TARBP1-ARID4B-20-GOGO | 20 (40 μL) | 200 μL |
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| TARBP1-ARID4B-20-GOGR | 20 (40 μL) | 200 μL |
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| TARBP1-ARID4B-20-GOAQ | 20 (40 μL) | 200 μL |
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| TARBP1-ARID4B-20-GRRE | 20 (40 μL) | 200 μL |
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| TARBP1-ARID4B-20-GROR | 20 (40 μL) | 200 μL |
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| TARBP1-ARID4B-20-GRGO | 20 (40 μL) | 200 μL |
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| TARBP1-ARID4B-20-GRGR | 20 (40 μL) | 200 μL |
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| TARBP1-ARID4B-20-GRAQ | 20 (40 μL) | 200 μL |
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| TARBP1-ARID4B-20-AQRE | 20 (40 μL) | 200 μL |
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| TARBP1-ARID4B-20-AQOR | 20 (40 μL) | 200 μL |
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| TARBP1-ARID4B-20-AQGO | 20 (40 μL) | 200 μL |
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| TARBP1-ARID4B-20-AQGR | 20 (40 μL) | 200 μL |
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| TARBP1-ARID4B-20-AQAQ | 20 (40 μL) | 200 μL |
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TARBP1 Gene Summary
HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. This element forms a stable stem-loop structure and can be bound by either the protein encoded by this gene or by RNA polymerase II. This protein may act to disengage RNA polymerase II from TAR during transcriptional elongation. Alternatively spliced transcripts of this gene may exist, but their full-length natures have not been determined. [provided by RefSeq, Jul 2008]
Gene Name: TAR (HIV-1) RNA Binding Protein 1
Chromosome: CHR1: 234527058 -234614849
Locus: 1q42.2
ARID4B Gene Summary
This gene encodes a protein with sequence similarity to retinoblastoma-binding protein-1. The encoded protein is a subunit of the histone deacetylase-dependant SIN3A transcriptional corepressor complex, which functions in diverse cellular processes including proliferation, differentiation, apoptosis, oncogenesis, and cell fate determination. The gene product is recognized by IgG antibody isolated from a breast cancer patient and appears to be a molecular marker associated with a broad range of human malignancies. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Jul 2008]
Gene Name: AT-rich Interaction Domain 4B
Chromosome: CHR1: 235330209 -235491532
Locus: 1q42.3
Gene Diseases
The TARBP1 ARID4B Fusion has been associated with the following diseases:
| Disease Name |
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| Pancreatic Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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