TALDO1-EPS8L2 Fusion FISH Probe
The TALDO1-EPS8L2 Fusion FISH Probe is used to confirm a fusion of the TALDO1 and EPS8L2 genes. The fusion of the TALDO1 and EPS8L2 genes has been associated with Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma, and Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TALDO1-EPS8L2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TALDO1-EPS8L2-20-RERE | 20 (40 μL) | 200 μL |
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| TALDO1-EPS8L2-20-REOR | 20 (40 μL) | 200 μL |
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| TALDO1-EPS8L2-20-REGO | 20 (40 μL) | 200 μL |
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| TALDO1-EPS8L2-20-REGR | 20 (40 μL) | 200 μL |
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| TALDO1-EPS8L2-20-REAQ | 20 (40 μL) | 200 μL |
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| TALDO1-EPS8L2-20-ORRE | 20 (40 μL) | 200 μL |
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| TALDO1-EPS8L2-20-OROR | 20 (40 μL) | 200 μL |
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| TALDO1-EPS8L2-20-ORGO | 20 (40 μL) | 200 μL |
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| TALDO1-EPS8L2-20-ORAQ | 20 (40 μL) | 200 μL |
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| TALDO1-EPS8L2-20-GORE | 20 (40 μL) | 200 μL |
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| TALDO1-EPS8L2-20-GOOR | 20 (40 μL) | 200 μL |
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| TALDO1-EPS8L2-20-GOGO | 20 (40 μL) | 200 μL |
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| TALDO1-EPS8L2-20-GOGR | 20 (40 μL) | 200 μL |
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| TALDO1-EPS8L2-20-GOAQ | 20 (40 μL) | 200 μL |
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| TALDO1-EPS8L2-20-GRRE | 20 (40 μL) | 200 μL |
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| TALDO1-EPS8L2-20-GROR | 20 (40 μL) | 200 μL |
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| TALDO1-EPS8L2-20-GRGO | 20 (40 μL) | 200 μL |
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| TALDO1-EPS8L2-20-GRGR | 20 (40 μL) | 200 μL |
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| TALDO1-EPS8L2-20-GRAQ | 20 (40 μL) | 200 μL |
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| TALDO1-EPS8L2-20-AQRE | 20 (40 μL) | 200 μL |
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| TALDO1-EPS8L2-20-AQOR | 20 (40 μL) | 200 μL |
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| TALDO1-EPS8L2-20-AQGO | 20 (40 μL) | 200 μL |
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| TALDO1-EPS8L2-20-AQGR | 20 (40 μL) | 200 μL |
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| TALDO1-EPS8L2-20-AQAQ | 20 (40 μL) | 200 μL |
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TALDO1 Gene Summary
Transaldolase 1 is a key enzyme of the nonoxidative pentose phosphate pathway providing ribose-5-phosphate for nucleic acid synthesis and NADPH for lipid biosynthesis. This pathway can also maintain glutathione at a reduced state and thus protect sulfhydryl groups and cellular integrity from oxygen radicals. The functional gene of transaldolase 1 is located on chromosome 11 and a pseudogene is identified on chromosome 1 but there are conflicting map locations. The second and third exon of this gene were developed by insertion of a retrotransposable element. This gene is thought to be involved in multiple sclerosis. [provided by RefSeq, Jul 2008]
Gene Name: Transaldolase 1
Chromosome: CHR11: 747431 -765024
Locus: 11p15.5
EPS8L2 Gene Summary
This gene encodes a member of the EPS8 gene family. The encoded protein, like other members of the family, is thought to link growth factor stimulation to actin organization, generating functional redundancy in the pathways that regulate actin cytoskeletal remodeling. [provided by RefSeq, Dec 2008]
Gene Name: EPS8 Like 2
Chromosome: CHR11: 706119 -727727
Locus: 11p15.5
Gene Diseases
The TALDO1 EPS8L2 Fusion has been associated with the following diseases:
| Disease Name |
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| Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma |
| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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