TAF8-CRISP1 Fusion FISH Probe
The TAF8-CRISP1 Fusion FISH Probe is used to confirm a fusion of the TAF8 and CRISP1 genes. The fusion of the TAF8 and CRISP1 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TAF8-CRISP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TAF8-CRISP1-20-RERE | 20 (40 μL) | 200 μL |
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| TAF8-CRISP1-20-REOR | 20 (40 μL) | 200 μL |
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| TAF8-CRISP1-20-REGO | 20 (40 μL) | 200 μL |
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| TAF8-CRISP1-20-REGR | 20 (40 μL) | 200 μL |
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| TAF8-CRISP1-20-REAQ | 20 (40 μL) | 200 μL |
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| TAF8-CRISP1-20-ORRE | 20 (40 μL) | 200 μL |
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| TAF8-CRISP1-20-OROR | 20 (40 μL) | 200 μL |
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| TAF8-CRISP1-20-ORGO | 20 (40 μL) | 200 μL |
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| TAF8-CRISP1-20-ORAQ | 20 (40 μL) | 200 μL |
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| TAF8-CRISP1-20-GORE | 20 (40 μL) | 200 μL |
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| TAF8-CRISP1-20-GOOR | 20 (40 μL) | 200 μL |
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| TAF8-CRISP1-20-GOGO | 20 (40 μL) | 200 μL |
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| TAF8-CRISP1-20-GOGR | 20 (40 μL) | 200 μL |
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| TAF8-CRISP1-20-GOAQ | 20 (40 μL) | 200 μL |
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| TAF8-CRISP1-20-GRRE | 20 (40 μL) | 200 μL |
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| TAF8-CRISP1-20-GROR | 20 (40 μL) | 200 μL |
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| TAF8-CRISP1-20-GRGO | 20 (40 μL) | 200 μL |
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| TAF8-CRISP1-20-GRGR | 20 (40 μL) | 200 μL |
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| TAF8-CRISP1-20-GRAQ | 20 (40 μL) | 200 μL |
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| TAF8-CRISP1-20-AQRE | 20 (40 μL) | 200 μL |
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| TAF8-CRISP1-20-AQOR | 20 (40 μL) | 200 μL |
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| TAF8-CRISP1-20-AQGO | 20 (40 μL) | 200 μL |
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| TAF8-CRISP1-20-AQGR | 20 (40 μL) | 200 μL |
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| TAF8-CRISP1-20-AQAQ | 20 (40 μL) | 200 μL |
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CRISP1 Gene Summary
Fertilization consists of a sequence of specific cell-cell interactions culminating in the fusion of the sperm and egg plasma membranes. Recognition, binding, and fusion occur through the interaction of complementary molecules that are localized to specific domains of the sperm and egg plasma membranes. In the sperm, the postacrosomal region or equatorial segment is involved in sperm-egg plasma membrane fusion. The protein encoded by this gene is a member of the cysteine-rich secretory protein (CRISP) family. It is expressed in the epididymis, is secreted into the epididymal lumen, and binds to the postacrosomal region of the sperm head, where it plays a role in sperm-egg fusion. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]
Gene Name: Cysteine Rich Secretory Protein 1
Chromosome: CHR6: 49801978 -49844809
Locus: 6p12.3
TAF8 Gene Summary
This gene encodes one of several TATA-binding protein (TBP)-associated factors (TAFs), which are integral subunits of the general transcription factor complex TFIID. TFIID recognizes the core promoter of many genes and nucleates the assembly of a transcription preinitiation complex containing RNA polymerase II and other initiation factors. The protein encoded by this gene contains an H4-like histone fold domain, and interacts with several subunits of TFIID including TBP and the histone-fold protein TAF10. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
Gene Name: TATA-box Binding Protein Associated Factor 8
Chromosome: CHR6: 42018250 -42048644
Locus: 6p21.1
Gene Diseases
The TAF8 CRISP1 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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