TAF8-COL5A3 Fusion FISH Probe
The TAF8-COL5A3 Fusion FISH Probe is used to confirm a fusion of the TAF8 and COL5A3 genes. The fusion of the TAF8 and COL5A3 genes has been associated with Brain Lower Grade Glioma, and Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TAF8-COL5A3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TAF8-COL5A3-20-RERE | 20 (40 μL) | 200 μL |
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| TAF8-COL5A3-20-REOR | 20 (40 μL) | 200 μL |
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| TAF8-COL5A3-20-REGO | 20 (40 μL) | 200 μL |
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| TAF8-COL5A3-20-REGR | 20 (40 μL) | 200 μL |
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| TAF8-COL5A3-20-REAQ | 20 (40 μL) | 200 μL |
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| TAF8-COL5A3-20-ORRE | 20 (40 μL) | 200 μL |
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| TAF8-COL5A3-20-OROR | 20 (40 μL) | 200 μL |
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| TAF8-COL5A3-20-ORGO | 20 (40 μL) | 200 μL |
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| TAF8-COL5A3-20-ORAQ | 20 (40 μL) | 200 μL |
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| TAF8-COL5A3-20-GORE | 20 (40 μL) | 200 μL |
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| TAF8-COL5A3-20-GOOR | 20 (40 μL) | 200 μL |
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| TAF8-COL5A3-20-GOGO | 20 (40 μL) | 200 μL |
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| TAF8-COL5A3-20-GOGR | 20 (40 μL) | 200 μL |
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| TAF8-COL5A3-20-GOAQ | 20 (40 μL) | 200 μL |
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| TAF8-COL5A3-20-GRRE | 20 (40 μL) | 200 μL |
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| TAF8-COL5A3-20-GROR | 20 (40 μL) | 200 μL |
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| TAF8-COL5A3-20-GRGO | 20 (40 μL) | 200 μL |
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| TAF8-COL5A3-20-GRGR | 20 (40 μL) | 200 μL |
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| TAF8-COL5A3-20-GRAQ | 20 (40 μL) | 200 μL |
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| TAF8-COL5A3-20-AQRE | 20 (40 μL) | 200 μL |
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| TAF8-COL5A3-20-AQOR | 20 (40 μL) | 200 μL |
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| TAF8-COL5A3-20-AQGO | 20 (40 μL) | 200 μL |
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| TAF8-COL5A3-20-AQGR | 20 (40 μL) | 200 μL |
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| TAF8-COL5A3-20-AQAQ | 20 (40 μL) | 200 μL |
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COL5A3 Gene Summary
This gene encodes an alpha chain for one of the low abundance fibrillar collagens. Fibrillar collagen molecules are trimers that can be composed of one or more types of alpha chains. Type V collagen is found in tissues containing type I collagen and appears to regulate the assembly of heterotypic fibers composed of both type I and type V collagen. This gene product is closely related to type XI collagen and it is possible that the collagen chains of types V and XI constitute a single collagen type with tissue-specific chain combinations. Mutations in this gene are thought to be responsible for the symptoms of a subset of patients with Ehlers-Danlos syndrome type III. Messages of several sizes can be detected in northern blots but sequence information cannot confirm the identity of the shorter messages. [provided by RefSeq, Jul 2008]
Gene Name: Collagen Type V Alpha 3 Chain
Chromosome: CHR19: 10070236 -10121147
Locus: 19p13.2
TAF8 Gene Summary
This gene encodes one of several TATA-binding protein (TBP)-associated factors (TAFs), which are integral subunits of the general transcription factor complex TFIID. TFIID recognizes the core promoter of many genes and nucleates the assembly of a transcription preinitiation complex containing RNA polymerase II and other initiation factors. The protein encoded by this gene contains an H4-like histone fold domain, and interacts with several subunits of TFIID including TBP and the histone-fold protein TAF10. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
Gene Name: TATA-box Binding Protein Associated Factor 8
Chromosome: CHR6: 42018250 -42048644
Locus: 6p21.1
Gene Diseases
The TAF8 COL5A3 Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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