TAF6L-TMEM109 Fusion FISH Probe
The TAF6L-TMEM109 Fusion FISH Probe is used to confirm a fusion of the TAF6L and TMEM109 genes. The fusion of the TAF6L and TMEM109 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TAF6L-TMEM109-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| TAF6L-TMEM109-20-RERE | 20 (40 μL) | 200 μL |
|
|
| TAF6L-TMEM109-20-REOR | 20 (40 μL) | 200 μL |
|
|
| TAF6L-TMEM109-20-REGO | 20 (40 μL) | 200 μL |
|
|
| TAF6L-TMEM109-20-REGR | 20 (40 μL) | 200 μL |
|
|
| TAF6L-TMEM109-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| TAF6L-TMEM109-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| TAF6L-TMEM109-20-OROR | 20 (40 μL) | 200 μL |
|
|
| TAF6L-TMEM109-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| TAF6L-TMEM109-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| TAF6L-TMEM109-20-GORE | 20 (40 μL) | 200 μL |
|
|
| TAF6L-TMEM109-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| TAF6L-TMEM109-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| TAF6L-TMEM109-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| TAF6L-TMEM109-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| TAF6L-TMEM109-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| TAF6L-TMEM109-20-GROR | 20 (40 μL) | 200 μL |
|
|
| TAF6L-TMEM109-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| TAF6L-TMEM109-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| TAF6L-TMEM109-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| TAF6L-TMEM109-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| TAF6L-TMEM109-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| TAF6L-TMEM109-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| TAF6L-TMEM109-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| TAF6L-TMEM109-20-AQAQ | 20 (40 μL) | 200 μL |
|
TAF6L Gene Summary
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a protein that is a component of the PCAF histone acetylase complex and structurally similar to one of the histone-like TAFs, TAF6. The PCAF histone acetylase complex, which is composed of more than 20 polypeptides some of which are TAFs, is required for myogenic transcription and differentiation. [provided by RefSeq, Jul 2008]
Gene Name: TATA-box Binding Protein Associated Factor 6 Like
Chromosome: CHR11: 62538774 -62554813
Locus: 11q12.3
TMEM109 Gene Summary
The Transmembrane Protein 109 (TMEM109) gene is located on chr11 :60681370-60690915 at 11q12.2.
Gene Name: Transmembrane Protein 109
Chromosome: CHR11: 60681370 -60690915
Locus: 11q12.2
Gene Diseases
The TAF6L TMEM109 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|