TAF1B-FOSL2 Fusion FISH Probe
The TAF1B-FOSL2 Fusion FISH Probe is used to confirm a fusion of the TAF1B and FOSL2 genes. The fusion of the TAF1B and FOSL2 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TAF1B-FOSL2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| TAF1B-FOSL2-20-RERE | 20 (40 μL) | 200 μL |
|
|
| TAF1B-FOSL2-20-REOR | 20 (40 μL) | 200 μL |
|
|
| TAF1B-FOSL2-20-REGO | 20 (40 μL) | 200 μL |
|
|
| TAF1B-FOSL2-20-REGR | 20 (40 μL) | 200 μL |
|
|
| TAF1B-FOSL2-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| TAF1B-FOSL2-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| TAF1B-FOSL2-20-OROR | 20 (40 μL) | 200 μL |
|
|
| TAF1B-FOSL2-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| TAF1B-FOSL2-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| TAF1B-FOSL2-20-GORE | 20 (40 μL) | 200 μL |
|
|
| TAF1B-FOSL2-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| TAF1B-FOSL2-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| TAF1B-FOSL2-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| TAF1B-FOSL2-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| TAF1B-FOSL2-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| TAF1B-FOSL2-20-GROR | 20 (40 μL) | 200 μL |
|
|
| TAF1B-FOSL2-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| TAF1B-FOSL2-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| TAF1B-FOSL2-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| TAF1B-FOSL2-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| TAF1B-FOSL2-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| TAF1B-FOSL2-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| TAF1B-FOSL2-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| TAF1B-FOSL2-20-AQAQ | 20 (40 μL) | 200 μL |
|
FOSL2 Gene Summary
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. [provided by RefSeq, Jul 2014]
Gene Name: FOS Like 2, AP-1 Transcription Factor Subunit
Chromosome: CHR2: 28615778 -28637516
Locus: 2p23.2
TAF1B Gene Summary
Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. This gene encodes one of the SL1-specific TAFs. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016]
Gene Name: TATA-box Binding Protein Associated Factor, RNA Polymerase I Subunit B
Chromosome: CHR2: 9983570 -10074545
Locus: 2p25.1
Gene Diseases
The TAF1B FOSL2 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|