TAF15-AP2B1 Fusion FISH Probe
The TAF15-AP2B1 Fusion FISH Probe is used to confirm a fusion of the TAF15 and AP2B1 genes. The fusion of the TAF15 and AP2B1 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TAF15-AP2B1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TAF15-AP2B1-20-RERE | 20 (40 μL) | 200 μL |
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| TAF15-AP2B1-20-REOR | 20 (40 μL) | 200 μL |
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| TAF15-AP2B1-20-REGO | 20 (40 μL) | 200 μL |
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| TAF15-AP2B1-20-REGR | 20 (40 μL) | 200 μL |
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| TAF15-AP2B1-20-REAQ | 20 (40 μL) | 200 μL |
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| TAF15-AP2B1-20-ORRE | 20 (40 μL) | 200 μL |
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| TAF15-AP2B1-20-OROR | 20 (40 μL) | 200 μL |
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| TAF15-AP2B1-20-ORGO | 20 (40 μL) | 200 μL |
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| TAF15-AP2B1-20-ORAQ | 20 (40 μL) | 200 μL |
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| TAF15-AP2B1-20-GORE | 20 (40 μL) | 200 μL |
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| TAF15-AP2B1-20-GOOR | 20 (40 μL) | 200 μL |
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| TAF15-AP2B1-20-GOGO | 20 (40 μL) | 200 μL |
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| TAF15-AP2B1-20-GOGR | 20 (40 μL) | 200 μL |
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| TAF15-AP2B1-20-GOAQ | 20 (40 μL) | 200 μL |
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| TAF15-AP2B1-20-GRRE | 20 (40 μL) | 200 μL |
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| TAF15-AP2B1-20-GROR | 20 (40 μL) | 200 μL |
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| TAF15-AP2B1-20-GRGO | 20 (40 μL) | 200 μL |
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| TAF15-AP2B1-20-GRGR | 20 (40 μL) | 200 μL |
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| TAF15-AP2B1-20-GRAQ | 20 (40 μL) | 200 μL |
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| TAF15-AP2B1-20-AQRE | 20 (40 μL) | 200 μL |
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| TAF15-AP2B1-20-AQOR | 20 (40 μL) | 200 μL |
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| TAF15-AP2B1-20-AQGO | 20 (40 μL) | 200 μL |
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| TAF15-AP2B1-20-AQGR | 20 (40 μL) | 200 μL |
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| TAF15-AP2B1-20-AQAQ | 20 (40 μL) | 200 μL |
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AP2B1 Gene Summary
The protein encoded by this gene is one of two large chain components of the assembly protein complex 2, which serves to link clathrin to receptors in coated vesicles. The encoded protein is found on the cytoplasmic face of coated vesicles in the plasma membrane. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Adaptor Related Protein Complex 2 Beta 1 Subunit
Chromosome: CHR17: 33914281 -34053436
Locus: 17q12
TAF15 Gene Summary
This gene encodes a member of the TET family of RNA-binding proteins. The encoded protein plays a role in RNA polymerase II gene transcription as a component of a distinct subset of multi-subunit transcription initiation factor TFIID complexes. Translocations involving this gene play a role in acute leukemia and extraskeletal myxoid chondrosarcoma, and mutations in this gene may play a role in amyotrophic lateral sclerosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]
Gene Name: TATA-box Binding Protein Associated Factor 15
Chromosome: CHR17: 34136487 -34174238
Locus: 17q12
Gene Diseases
The TAF15 AP2B1 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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