SYNRG-ROBO1 Fusion FISH Probe
The SYNRG-ROBO1 Fusion FISH Probe is used to confirm a fusion of the SYNRG and ROBO1 genes. The fusion of the SYNRG and ROBO1 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SYNRG-ROBO1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SYNRG-ROBO1-20-RERE | 20 (40 μL) | 200 μL |
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| SYNRG-ROBO1-20-REOR | 20 (40 μL) | 200 μL |
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| SYNRG-ROBO1-20-REGO | 20 (40 μL) | 200 μL |
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| SYNRG-ROBO1-20-REGR | 20 (40 μL) | 200 μL |
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| SYNRG-ROBO1-20-REAQ | 20 (40 μL) | 200 μL |
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| SYNRG-ROBO1-20-ORRE | 20 (40 μL) | 200 μL |
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| SYNRG-ROBO1-20-OROR | 20 (40 μL) | 200 μL |
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| SYNRG-ROBO1-20-ORGO | 20 (40 μL) | 200 μL |
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| SYNRG-ROBO1-20-ORAQ | 20 (40 μL) | 200 μL |
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| SYNRG-ROBO1-20-GORE | 20 (40 μL) | 200 μL |
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| SYNRG-ROBO1-20-GOOR | 20 (40 μL) | 200 μL |
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| SYNRG-ROBO1-20-GOGO | 20 (40 μL) | 200 μL |
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| SYNRG-ROBO1-20-GOGR | 20 (40 μL) | 200 μL |
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| SYNRG-ROBO1-20-GOAQ | 20 (40 μL) | 200 μL |
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| SYNRG-ROBO1-20-GRRE | 20 (40 μL) | 200 μL |
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| SYNRG-ROBO1-20-GROR | 20 (40 μL) | 200 μL |
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| SYNRG-ROBO1-20-GRGO | 20 (40 μL) | 200 μL |
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| SYNRG-ROBO1-20-GRGR | 20 (40 μL) | 200 μL |
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| SYNRG-ROBO1-20-GRAQ | 20 (40 μL) | 200 μL |
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| SYNRG-ROBO1-20-AQRE | 20 (40 μL) | 200 μL |
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| SYNRG-ROBO1-20-AQOR | 20 (40 μL) | 200 μL |
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| SYNRG-ROBO1-20-AQGO | 20 (40 μL) | 200 μL |
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| SYNRG-ROBO1-20-AQGR | 20 (40 μL) | 200 μL |
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| SYNRG-ROBO1-20-AQAQ | 20 (40 μL) | 200 μL |
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ROBO1 Gene Summary
Bilateral symmetric nervous systems have special midline structures that establish a partition between the two mirror image halves. Some axons project toward and across the midline in response to long-range chemoattractants emanating from the midline. The product of this gene is a member of the immunoglobulin gene superfamily and encodes an integral membrane protein that functions in axon guidance and neuronal precursor cell migration. This receptor is activated by SLIT-family proteins, resulting in a repulsive effect on glioma cell guidance in the developing brain. A related gene is located at an adjacent region on chromosome 3. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
Gene Name: Roundabout Guidance Receptor 1
Chromosome: CHR3: 78646387 -79817059
Locus: 3p12.3
SYNRG Gene Summary
This gene encodes a protein that interacts with the gamma subunit of AP1 clathrin-adaptor complex. The AP1 complex is located at the trans-Golgi network and associates specific proteins with clathrin-coated vesicles. This encoded protein may act to connect the AP1 complex to other proteins. Alternatively spliced transcript variants that encode different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Synergin Gamma
Chromosome: CHR17: 35874899 -35969486
Locus: 17q12
Gene Diseases
The SYNRG ROBO1 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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