SYNRG-AATF Fusion FISH Probe
The SYNRG-AATF Fusion FISH Probe is used to confirm a fusion of the SYNRG and AATF genes. The fusion of the SYNRG and AATF genes has been associated with Mesothelioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SYNRG-AATF-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SYNRG-AATF-20-RERE | 20 (40 μL) | 200 μL |
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| SYNRG-AATF-20-REOR | 20 (40 μL) | 200 μL |
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| SYNRG-AATF-20-REGO | 20 (40 μL) | 200 μL |
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| SYNRG-AATF-20-REGR | 20 (40 μL) | 200 μL |
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| SYNRG-AATF-20-REAQ | 20 (40 μL) | 200 μL |
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| SYNRG-AATF-20-ORRE | 20 (40 μL) | 200 μL |
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| SYNRG-AATF-20-OROR | 20 (40 μL) | 200 μL |
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| SYNRG-AATF-20-ORGO | 20 (40 μL) | 200 μL |
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| SYNRG-AATF-20-ORAQ | 20 (40 μL) | 200 μL |
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| SYNRG-AATF-20-GORE | 20 (40 μL) | 200 μL |
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| SYNRG-AATF-20-GOOR | 20 (40 μL) | 200 μL |
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| SYNRG-AATF-20-GOGO | 20 (40 μL) | 200 μL |
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| SYNRG-AATF-20-GOGR | 20 (40 μL) | 200 μL |
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| SYNRG-AATF-20-GOAQ | 20 (40 μL) | 200 μL |
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| SYNRG-AATF-20-GRRE | 20 (40 μL) | 200 μL |
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| SYNRG-AATF-20-GROR | 20 (40 μL) | 200 μL |
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| SYNRG-AATF-20-GRGO | 20 (40 μL) | 200 μL |
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| SYNRG-AATF-20-GRGR | 20 (40 μL) | 200 μL |
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| SYNRG-AATF-20-GRAQ | 20 (40 μL) | 200 μL |
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| SYNRG-AATF-20-AQRE | 20 (40 μL) | 200 μL |
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| SYNRG-AATF-20-AQOR | 20 (40 μL) | 200 μL |
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| SYNRG-AATF-20-AQGO | 20 (40 μL) | 200 μL |
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| SYNRG-AATF-20-AQGR | 20 (40 μL) | 200 μL |
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| SYNRG-AATF-20-AQAQ | 20 (40 μL) | 200 μL |
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SYNRG Gene Summary
This gene encodes a protein that interacts with the gamma subunit of AP1 clathrin-adaptor complex. The AP1 complex is located at the trans-Golgi network and associates specific proteins with clathrin-coated vesicles. This encoded protein may act to connect the AP1 complex to other proteins. Alternatively spliced transcript variants that encode different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Synergin Gamma
Chromosome: CHR17: 35874899 -35969486
Locus: 17q12
AATF Gene Summary
The protein encoded by this gene was identified on the basis of its interaction with MAP3K12/DLK, a protein kinase known to be involved in the induction of cell apoptosis. This gene product contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of this gene interfered with MAP3K12 induced apoptosis. [provided by RefSeq, Jul 2008]
Gene Name: Apoptosis Antagonizing Transcription Factor
Chromosome: CHR17: 35306174 -35414171
Locus: 17q12
Gene Diseases
The SYNRG AATF Fusion has been associated with the following diseases:
| Disease Name |
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| Mesothelioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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