SYNE2-ITPK1 Fusion FISH Probe
The SYNE2-ITPK1 Fusion FISH Probe is used to confirm a fusion of the SYNE2 and ITPK1 genes. The fusion of the SYNE2 and ITPK1 genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SYNE2-ITPK1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SYNE2-ITPK1-20-RERE | 20 (40 μL) | 200 μL |
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| SYNE2-ITPK1-20-REOR | 20 (40 μL) | 200 μL |
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| SYNE2-ITPK1-20-REGO | 20 (40 μL) | 200 μL |
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| SYNE2-ITPK1-20-REGR | 20 (40 μL) | 200 μL |
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| SYNE2-ITPK1-20-REAQ | 20 (40 μL) | 200 μL |
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| SYNE2-ITPK1-20-ORRE | 20 (40 μL) | 200 μL |
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| SYNE2-ITPK1-20-OROR | 20 (40 μL) | 200 μL |
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| SYNE2-ITPK1-20-ORGO | 20 (40 μL) | 200 μL |
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| SYNE2-ITPK1-20-ORAQ | 20 (40 μL) | 200 μL |
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| SYNE2-ITPK1-20-GORE | 20 (40 μL) | 200 μL |
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| SYNE2-ITPK1-20-GOOR | 20 (40 μL) | 200 μL |
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| SYNE2-ITPK1-20-GOGO | 20 (40 μL) | 200 μL |
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| SYNE2-ITPK1-20-GOGR | 20 (40 μL) | 200 μL |
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| SYNE2-ITPK1-20-GOAQ | 20 (40 μL) | 200 μL |
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| SYNE2-ITPK1-20-GRRE | 20 (40 μL) | 200 μL |
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| SYNE2-ITPK1-20-GROR | 20 (40 μL) | 200 μL |
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| SYNE2-ITPK1-20-GRGO | 20 (40 μL) | 200 μL |
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| SYNE2-ITPK1-20-GRGR | 20 (40 μL) | 200 μL |
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| SYNE2-ITPK1-20-GRAQ | 20 (40 μL) | 200 μL |
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| SYNE2-ITPK1-20-AQRE | 20 (40 μL) | 200 μL |
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| SYNE2-ITPK1-20-AQOR | 20 (40 μL) | 200 μL |
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| SYNE2-ITPK1-20-AQGO | 20 (40 μL) | 200 μL |
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| SYNE2-ITPK1-20-AQGR | 20 (40 μL) | 200 μL |
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| SYNE2-ITPK1-20-AQAQ | 20 (40 μL) | 200 μL |
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ITPK1 Gene Summary
This gene encodes an enzyme that belongs to the inositol 1,3,4-trisphosphate 5/6-kinase family. This enzyme regulates the synthesis of inositol tetraphosphate, and downstream products, inositol pentakisphosphate and inositol hexakisphosphate. Inositol metabolism plays a role in the development of the neural tube. Disruptions in this gene are thought to be associated with neural tube defects. A pseudogene of this gene has been identified on chromosome X. [provided by RefSeq, Jul 2016]
Gene Name: Inositol-tetrakisphosphate 1-kinase
Chromosome: CHR14: 93403258 -93582263
Locus: 14q32.12
SYNE2 Gene Summary
The protein encoded by this gene is a nuclear outer membrane protein that binds cytoplasmic F-actin. This binding tethers the nucleus to the cytoskeleton and aids in the maintenance of the structural integrity of the nucleus. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
Gene Name: Spectrin Repeat Containing Nuclear Envelope Protein 2
Chromosome: CHR14: 64319682 -64693167
Locus: 14q23.2
Gene Diseases
The SYNE2 ITPK1 Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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