SYF2-RHD Fusion FISH Probe
The SYF2-RHD Fusion FISH Probe is used to confirm a fusion of the SYF2 and RHD genes. The fusion of the SYF2 and RHD genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SYF2-RHD-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SYF2-RHD-20-RERE | 20 (40 μL) | 200 μL |
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| SYF2-RHD-20-REOR | 20 (40 μL) | 200 μL |
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| SYF2-RHD-20-REGO | 20 (40 μL) | 200 μL |
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| SYF2-RHD-20-REGR | 20 (40 μL) | 200 μL |
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| SYF2-RHD-20-REAQ | 20 (40 μL) | 200 μL |
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| SYF2-RHD-20-ORRE | 20 (40 μL) | 200 μL |
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| SYF2-RHD-20-OROR | 20 (40 μL) | 200 μL |
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| SYF2-RHD-20-ORGO | 20 (40 μL) | 200 μL |
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| SYF2-RHD-20-ORAQ | 20 (40 μL) | 200 μL |
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| SYF2-RHD-20-GORE | 20 (40 μL) | 200 μL |
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| SYF2-RHD-20-GOOR | 20 (40 μL) | 200 μL |
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| SYF2-RHD-20-GOGO | 20 (40 μL) | 200 μL |
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| SYF2-RHD-20-GOGR | 20 (40 μL) | 200 μL |
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| SYF2-RHD-20-GOAQ | 20 (40 μL) | 200 μL |
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| SYF2-RHD-20-GRRE | 20 (40 μL) | 200 μL |
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| SYF2-RHD-20-GROR | 20 (40 μL) | 200 μL |
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| SYF2-RHD-20-GRGO | 20 (40 μL) | 200 μL |
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| SYF2-RHD-20-GRGR | 20 (40 μL) | 200 μL |
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| SYF2-RHD-20-GRAQ | 20 (40 μL) | 200 μL |
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| SYF2-RHD-20-AQRE | 20 (40 μL) | 200 μL |
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| SYF2-RHD-20-AQOR | 20 (40 μL) | 200 μL |
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| SYF2-RHD-20-AQGO | 20 (40 μL) | 200 μL |
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| SYF2-RHD-20-AQGR | 20 (40 μL) | 200 μL |
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| SYF2-RHD-20-AQAQ | 20 (40 μL) | 200 μL |
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RHD Gene Summary
The Rh blood group system is the second most clinically significant of the blood groups, second only to ABO. It is also the most polymorphic of the blood groups, with variations due to deletions, gene conversions, and missense mutations. The Rh blood group includes this gene, which encodes the RhD protein, and a second gene that encodes both the RhC and RhE antigens on a single polypeptide. The two genes, and a third unrelated gene, are found in a cluster on chromosome 1. The classification of Rh-positive and Rh-negative individuals is determined by the presence or absence of the highly immunogenic RhD protein on the surface of erythrocytes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Rh Blood Group D Antigen
Chromosome: CHR1: 25598980 -25656936
Locus: 1p36.11
SYF2 Gene Summary
This gene encodes a nuclear protein that interacts with cyclin D-type binding-protein 1, which is thought to be a cell cycle regulator at the G1/S transition. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Gene Name: SYF2 Pre-mRNA Splicing Factor
Chromosome: CHR1: 25548766 -25559013
Locus: 1p36.11
Gene Diseases
The SYF2 RHD Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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