SUZ12-ADAP2 Fusion FISH Probe
The SUZ12-ADAP2 Fusion FISH Probe is used to confirm a fusion of the SUZ12 and ADAP2 genes. The fusion of the SUZ12 and ADAP2 genes has been associated with Uterine Carcinosarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SUZ12-ADAP2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SUZ12-ADAP2-20-RERE | 20 (40 μL) | 200 μL |
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| SUZ12-ADAP2-20-REOR | 20 (40 μL) | 200 μL |
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| SUZ12-ADAP2-20-REGO | 20 (40 μL) | 200 μL |
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| SUZ12-ADAP2-20-REGR | 20 (40 μL) | 200 μL |
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| SUZ12-ADAP2-20-REAQ | 20 (40 μL) | 200 μL |
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| SUZ12-ADAP2-20-ORRE | 20 (40 μL) | 200 μL |
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| SUZ12-ADAP2-20-OROR | 20 (40 μL) | 200 μL |
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| SUZ12-ADAP2-20-ORGO | 20 (40 μL) | 200 μL |
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| SUZ12-ADAP2-20-ORAQ | 20 (40 μL) | 200 μL |
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| SUZ12-ADAP2-20-GORE | 20 (40 μL) | 200 μL |
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| SUZ12-ADAP2-20-GOOR | 20 (40 μL) | 200 μL |
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| SUZ12-ADAP2-20-GOGO | 20 (40 μL) | 200 μL |
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| SUZ12-ADAP2-20-GOGR | 20 (40 μL) | 200 μL |
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| SUZ12-ADAP2-20-GOAQ | 20 (40 μL) | 200 μL |
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| SUZ12-ADAP2-20-GRRE | 20 (40 μL) | 200 μL |
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| SUZ12-ADAP2-20-GROR | 20 (40 μL) | 200 μL |
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| SUZ12-ADAP2-20-GRGO | 20 (40 μL) | 200 μL |
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| SUZ12-ADAP2-20-GRGR | 20 (40 μL) | 200 μL |
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| SUZ12-ADAP2-20-GRAQ | 20 (40 μL) | 200 μL |
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| SUZ12-ADAP2-20-AQRE | 20 (40 μL) | 200 μL |
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| SUZ12-ADAP2-20-AQOR | 20 (40 μL) | 200 μL |
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| SUZ12-ADAP2-20-AQGO | 20 (40 μL) | 200 μL |
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| SUZ12-ADAP2-20-AQGR | 20 (40 μL) | 200 μL |
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| SUZ12-ADAP2-20-AQAQ | 20 (40 μL) | 200 μL |
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SUZ12 Gene Summary
This zinc finger gene has been identified at the breakpoints of a recurrent chromosomal translocation reported in endometrial stromal sarcoma. Recombination of these breakpoints results in the fusion of this gene and JAZF1. The protein encoded by this gene contains a zinc finger domain in the C terminus of the coding region. [provided by RefSeq, Jul 2009]
Gene Name: SUZ12 Polycomb Repressive Complex 2 Subunit
Chromosome: CHR17: 30264043 -30328057
Locus: 17q11.2
ADAP2 Gene Summary
The protein encoded by this gene binds beta-tubulin and increases the stability of microtubules. The encoded protein can also translocate to the cell membrane and bind phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and inositol 1,3,4,5-tetrakisphosphate (InsP4). In addition, this protein is a GTPase-activating protein for ADP ribosylation factor 6 and may be able to block the entry of some RNA viruses. [provided by RefSeq, Oct 2016]
Gene Name: ArfGAP With Dual PH Domains 2
Chromosome: CHR17: 29248753 -29286211
Locus: 17q11.2
Gene Diseases
The SUZ12 ADAP2 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Carcinosarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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