SULF1-C8ORF34 Fusion FISH Probe
The SULF1-C8ORF34 Fusion FISH Probe is used to confirm a fusion of the SULF1 and C8ORF34 genes. The fusion of the SULF1 and C8ORF34 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SULF1-C8ORF34-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SULF1-C8ORF34-20-RERE | 20 (40 μL) | 200 μL |
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| SULF1-C8ORF34-20-REOR | 20 (40 μL) | 200 μL |
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| SULF1-C8ORF34-20-REGO | 20 (40 μL) | 200 μL |
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| SULF1-C8ORF34-20-REGR | 20 (40 μL) | 200 μL |
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| SULF1-C8ORF34-20-REAQ | 20 (40 μL) | 200 μL |
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| SULF1-C8ORF34-20-ORRE | 20 (40 μL) | 200 μL |
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| SULF1-C8ORF34-20-OROR | 20 (40 μL) | 200 μL |
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| SULF1-C8ORF34-20-ORGO | 20 (40 μL) | 200 μL |
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| SULF1-C8ORF34-20-ORAQ | 20 (40 μL) | 200 μL |
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| SULF1-C8ORF34-20-GORE | 20 (40 μL) | 200 μL |
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| SULF1-C8ORF34-20-GOOR | 20 (40 μL) | 200 μL |
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| SULF1-C8ORF34-20-GOGO | 20 (40 μL) | 200 μL |
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| SULF1-C8ORF34-20-GOGR | 20 (40 μL) | 200 μL |
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| SULF1-C8ORF34-20-GOAQ | 20 (40 μL) | 200 μL |
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| SULF1-C8ORF34-20-GRRE | 20 (40 μL) | 200 μL |
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| SULF1-C8ORF34-20-GROR | 20 (40 μL) | 200 μL |
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| SULF1-C8ORF34-20-GRGO | 20 (40 μL) | 200 μL |
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| SULF1-C8ORF34-20-GRGR | 20 (40 μL) | 200 μL |
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| SULF1-C8ORF34-20-GRAQ | 20 (40 μL) | 200 μL |
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| SULF1-C8ORF34-20-AQRE | 20 (40 μL) | 200 μL |
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| SULF1-C8ORF34-20-AQOR | 20 (40 μL) | 200 μL |
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| SULF1-C8ORF34-20-AQGO | 20 (40 μL) | 200 μL |
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| SULF1-C8ORF34-20-AQGR | 20 (40 μL) | 200 μL |
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| SULF1-C8ORF34-20-AQAQ | 20 (40 μL) | 200 μL |
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SULF1 Gene Summary
This gene encodes an extracellular heparan sulfate endosulfatase. The encoded enzyme selectively removes 6-O-sulfate groups from heparan sulfate chains of heparan sulfate proteoglycans (HSPGs). The enzyme is secreted through the Golgi and is subsequently localized to the cell surface. The expression of this gene may be down-regulated in several types of cancer, including hepatocellular (HCC), ovarian and breast cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
Gene Name: Sulfatase 1
Chromosome: CHR8: 70378858 -70573147
Locus: 8q13.2-q13.3
C8orf34 Gene Summary
This gene encodes a protein that is related to the cyclic AMP dependent protein kinase regulators. Naturally occurring mutations in this gene are associated with an increased risk for severe toxicities, such as diarrhea and neutropenia, in patients undergoing chemotherapeutic treatment. [provided by RefSeq, Mar 2017]
Gene Name: Chromosome 8 Open Reading Frame 34
Chromosome: CHR8: 69242956 -69731258
Locus: 8q13.2
Gene Diseases
The SULF1 C8ORF34 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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