SUFU-ADK Fusion FISH Probe
The SUFU-ADK Fusion FISH Probe is used to confirm a fusion of the SUFU and ADK genes. The fusion of the SUFU and ADK genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SUFU-ADK-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SUFU-ADK-20-RERE | 20 (40 μL) | 200 μL |
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| SUFU-ADK-20-REOR | 20 (40 μL) | 200 μL |
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| SUFU-ADK-20-REGO | 20 (40 μL) | 200 μL |
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| SUFU-ADK-20-REGR | 20 (40 μL) | 200 μL |
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| SUFU-ADK-20-REAQ | 20 (40 μL) | 200 μL |
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| SUFU-ADK-20-ORRE | 20 (40 μL) | 200 μL |
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| SUFU-ADK-20-OROR | 20 (40 μL) | 200 μL |
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| SUFU-ADK-20-ORGO | 20 (40 μL) | 200 μL |
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| SUFU-ADK-20-ORAQ | 20 (40 μL) | 200 μL |
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| SUFU-ADK-20-GORE | 20 (40 μL) | 200 μL |
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| SUFU-ADK-20-GOOR | 20 (40 μL) | 200 μL |
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| SUFU-ADK-20-GOGO | 20 (40 μL) | 200 μL |
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| SUFU-ADK-20-GOGR | 20 (40 μL) | 200 μL |
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| SUFU-ADK-20-GOAQ | 20 (40 μL) | 200 μL |
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| SUFU-ADK-20-GRRE | 20 (40 μL) | 200 μL |
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| SUFU-ADK-20-GROR | 20 (40 μL) | 200 μL |
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| SUFU-ADK-20-GRGO | 20 (40 μL) | 200 μL |
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| SUFU-ADK-20-GRGR | 20 (40 μL) | 200 μL |
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| SUFU-ADK-20-GRAQ | 20 (40 μL) | 200 μL |
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| SUFU-ADK-20-AQRE | 20 (40 μL) | 200 μL |
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| SUFU-ADK-20-AQOR | 20 (40 μL) | 200 μL |
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| SUFU-ADK-20-AQGO | 20 (40 μL) | 200 μL |
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| SUFU-ADK-20-AQGR | 20 (40 μL) | 200 μL |
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| SUFU-ADK-20-AQAQ | 20 (40 μL) | 200 μL |
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ADK Gene Summary
This gene an enzyme which catalyzes the transfer of the gamma-phosphate from ATP to adenosine, thereby serving as a regulator of concentrations of both extracellular adenosine and intracellular adenine nucleotides. Adenosine has widespread effects on the cardiovascular, nervous, respiratory, and immune systems and inhibitors of the enzyme could play an important pharmacological role in increasing intravascular adenosine concentrations and acting as anti-inflammatory agents. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011]
Gene Name: Adenosine Kinase
Chromosome: CHR10: 75910942 -76469061
Locus: 10q11-q24
SUFU Gene Summary
The Hedgehog signaling pathway plays an important role in early human development. The pathway is a signaling cascade that plays a role in pattern formation and cellular proliferation during development. This gene encodes a negative regulator of the hedgehog signaling pathway. Defects in this gene are a cause of medulloblastoma. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
Gene Name: SUFU Negative Regulator Of Hedgehog Signaling
Chromosome: CHR10: 104263718 -104393214
Locus: 10q24.32
Gene Diseases
The SUFU ADK Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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