STX17-NR4A3 Fusion FISH Probe
The STX17-NR4A3 Fusion FISH Probe is used to confirm a fusion of the STX17 and NR4A3 genes. The fusion of the STX17 and NR4A3 genes has been associated with Lung Squamous Cell Carcinoma, and Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| STX17-NR4A3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| STX17-NR4A3-20-RERE | 20 (40 μL) | 200 μL |
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| STX17-NR4A3-20-REOR | 20 (40 μL) | 200 μL |
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| STX17-NR4A3-20-REGO | 20 (40 μL) | 200 μL |
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| STX17-NR4A3-20-REGR | 20 (40 μL) | 200 μL |
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| STX17-NR4A3-20-REAQ | 20 (40 μL) | 200 μL |
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| STX17-NR4A3-20-ORRE | 20 (40 μL) | 200 μL |
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| STX17-NR4A3-20-OROR | 20 (40 μL) | 200 μL |
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| STX17-NR4A3-20-ORGO | 20 (40 μL) | 200 μL |
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| STX17-NR4A3-20-ORAQ | 20 (40 μL) | 200 μL |
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| STX17-NR4A3-20-GORE | 20 (40 μL) | 200 μL |
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| STX17-NR4A3-20-GOOR | 20 (40 μL) | 200 μL |
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| STX17-NR4A3-20-GOGO | 20 (40 μL) | 200 μL |
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| STX17-NR4A3-20-GOGR | 20 (40 μL) | 200 μL |
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| STX17-NR4A3-20-GOAQ | 20 (40 μL) | 200 μL |
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| STX17-NR4A3-20-GRRE | 20 (40 μL) | 200 μL |
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| STX17-NR4A3-20-GROR | 20 (40 μL) | 200 μL |
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| STX17-NR4A3-20-GRGO | 20 (40 μL) | 200 μL |
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| STX17-NR4A3-20-GRGR | 20 (40 μL) | 200 μL |
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| STX17-NR4A3-20-GRAQ | 20 (40 μL) | 200 μL |
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| STX17-NR4A3-20-AQRE | 20 (40 μL) | 200 μL |
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| STX17-NR4A3-20-AQOR | 20 (40 μL) | 200 μL |
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| STX17-NR4A3-20-AQGO | 20 (40 μL) | 200 μL |
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| STX17-NR4A3-20-AQGR | 20 (40 μL) | 200 μL |
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| STX17-NR4A3-20-AQAQ | 20 (40 μL) | 200 μL |
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NR4A3 Gene Summary
This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as a transcriptional activator. The protein can efficiently bind the NGFI-B Response Element (NBRE). Three different versions of extraskeletal myxoid chondrosarcomas (EMCs) are the result of reciprocal translocations between this gene and other genes. The translocation breakpoints are associated with Nuclear Receptor Subfamily 4, Group A, Member 3 (on chromosome 9) and either Ewing Sarcome Breakpoint Region 1 (on chromosome 22), RNA Polymerase II, TATA Box-Binding Protein-Associated Factor, 68-KD (on chromosome 17), or Transcription factor 12 (on chromosome 15). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]
Gene Name: Nuclear Receptor Subfamily 4 Group A Member 3
Chromosome: CHR9: 102584136 -102629173
Locus: 9q31.1
STX17 Gene Summary
The Syntaxin 17 (STX17) gene is located on chr9 :102668914-102736818 at 9q31.1.
Gene Name: Syntaxin 17
Chromosome: CHR9: 102668914 -102736818
Locus: 9q31.1
Gene Diseases
The STX17 NR4A3 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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