STK39-SCN3A Fusion FISH Probe
The STK39-SCN3A Fusion FISH Probe is used to confirm a fusion of the STK39 and SCN3A genes. The fusion of the STK39 and SCN3A genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| STK39-SCN3A-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| STK39-SCN3A-20-RERE | 20 (40 μL) | 200 μL |
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| STK39-SCN3A-20-REOR | 20 (40 μL) | 200 μL |
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| STK39-SCN3A-20-REGO | 20 (40 μL) | 200 μL |
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| STK39-SCN3A-20-REGR | 20 (40 μL) | 200 μL |
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| STK39-SCN3A-20-REAQ | 20 (40 μL) | 200 μL |
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| STK39-SCN3A-20-ORRE | 20 (40 μL) | 200 μL |
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| STK39-SCN3A-20-OROR | 20 (40 μL) | 200 μL |
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| STK39-SCN3A-20-ORGO | 20 (40 μL) | 200 μL |
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| STK39-SCN3A-20-ORAQ | 20 (40 μL) | 200 μL |
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| STK39-SCN3A-20-GORE | 20 (40 μL) | 200 μL |
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| STK39-SCN3A-20-GOOR | 20 (40 μL) | 200 μL |
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| STK39-SCN3A-20-GOGO | 20 (40 μL) | 200 μL |
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| STK39-SCN3A-20-GOGR | 20 (40 μL) | 200 μL |
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| STK39-SCN3A-20-GOAQ | 20 (40 μL) | 200 μL |
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| STK39-SCN3A-20-GRRE | 20 (40 μL) | 200 μL |
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| STK39-SCN3A-20-GROR | 20 (40 μL) | 200 μL |
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| STK39-SCN3A-20-GRGO | 20 (40 μL) | 200 μL |
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| STK39-SCN3A-20-GRGR | 20 (40 μL) | 200 μL |
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| STK39-SCN3A-20-GRAQ | 20 (40 μL) | 200 μL |
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| STK39-SCN3A-20-AQRE | 20 (40 μL) | 200 μL |
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| STK39-SCN3A-20-AQOR | 20 (40 μL) | 200 μL |
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| STK39-SCN3A-20-AQGO | 20 (40 μL) | 200 μL |
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| STK39-SCN3A-20-AQGR | 20 (40 μL) | 200 μL |
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| STK39-SCN3A-20-AQAQ | 20 (40 μL) | 200 μL |
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SCN3A Gene Summary
Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with 24 transmembrane domains and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel alpha subunit gene family, and is found in a cluster of five alpha subunit genes on chromosome 2. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Sodium Voltage-gated Channel Alpha Subunit 3
Chromosome: CHR2: 165944029 -166060577
Locus: 2q24.3
STK39 Gene Summary
This gene encodes a serine/threonine kinase that is thought to function in the cellular stress response pathway. The kinase is activated in response to hypotonic stress, leading to phosphorylation of several cation-chloride-coupled cotransporters. The catalytically active kinase specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the response to cellular stress. [provided by RefSeq, Jul 2008]
Gene Name: Serine/threonine Kinase 39
Chromosome: CHR2: 168810529 -169104105
Locus: 2q24.3
Gene Diseases
The STK39 SCN3A Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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