STK39-MAT1A Fusion FISH Probe
The STK39-MAT1A Fusion FISH Probe is used to confirm a fusion of the STK39 and MAT1A genes. The fusion of the STK39 and MAT1A genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| STK39-MAT1A-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| STK39-MAT1A-20-RERE | 20 (40 μL) | 200 μL |
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| STK39-MAT1A-20-REOR | 20 (40 μL) | 200 μL |
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| STK39-MAT1A-20-REGO | 20 (40 μL) | 200 μL |
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| STK39-MAT1A-20-REGR | 20 (40 μL) | 200 μL |
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| STK39-MAT1A-20-REAQ | 20 (40 μL) | 200 μL |
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| STK39-MAT1A-20-ORRE | 20 (40 μL) | 200 μL |
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| STK39-MAT1A-20-OROR | 20 (40 μL) | 200 μL |
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| STK39-MAT1A-20-ORGO | 20 (40 μL) | 200 μL |
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| STK39-MAT1A-20-ORAQ | 20 (40 μL) | 200 μL |
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| STK39-MAT1A-20-GORE | 20 (40 μL) | 200 μL |
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| STK39-MAT1A-20-GOOR | 20 (40 μL) | 200 μL |
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| STK39-MAT1A-20-GOGO | 20 (40 μL) | 200 μL |
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| STK39-MAT1A-20-GOGR | 20 (40 μL) | 200 μL |
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| STK39-MAT1A-20-GOAQ | 20 (40 μL) | 200 μL |
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| STK39-MAT1A-20-GRRE | 20 (40 μL) | 200 μL |
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| STK39-MAT1A-20-GROR | 20 (40 μL) | 200 μL |
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| STK39-MAT1A-20-GRGO | 20 (40 μL) | 200 μL |
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| STK39-MAT1A-20-GRGR | 20 (40 μL) | 200 μL |
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| STK39-MAT1A-20-GRAQ | 20 (40 μL) | 200 μL |
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| STK39-MAT1A-20-AQRE | 20 (40 μL) | 200 μL |
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| STK39-MAT1A-20-AQOR | 20 (40 μL) | 200 μL |
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| STK39-MAT1A-20-AQGO | 20 (40 μL) | 200 μL |
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| STK39-MAT1A-20-AQGR | 20 (40 μL) | 200 μL |
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| STK39-MAT1A-20-AQAQ | 20 (40 μL) | 200 μL |
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MAT1A Gene Summary
This gene catalyzes a two-step reaction that involves the transfer of the adenosyl moiety of ATP to methionine to form S-adenosylmethionine and tripolyphosphate, which is subsequently cleaved to PPi and Pi. S-adenosylmethionine is the source of methyl groups for most biological methylations. The encoded protein is found as a homotetramer (MAT I) or a homodimer (MAT III) whereas a third form, MAT II (gamma), is encoded by the MAT2A gene. Mutations in this gene are associated with methionine adenosyltransferase deficiency. [provided by RefSeq, Jul 2008]
Gene Name: Methionine Adenosyltransferase 1A
Chromosome: CHR10: 82031575 -82049434
Locus: 10q22.3
STK39 Gene Summary
This gene encodes a serine/threonine kinase that is thought to function in the cellular stress response pathway. The kinase is activated in response to hypotonic stress, leading to phosphorylation of several cation-chloride-coupled cotransporters. The catalytically active kinase specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the response to cellular stress. [provided by RefSeq, Jul 2008]
Gene Name: Serine/threonine Kinase 39
Chromosome: CHR2: 168810529 -169104105
Locus: 2q24.3
Gene Diseases
The STK39 MAT1A Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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