STK3-ZHX2 Fusion FISH Probe
The STK3-ZHX2 Fusion FISH Probe is used to confirm a fusion of the STK3 and ZHX2 genes. The fusion of the STK3 and ZHX2 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| STK3-ZHX2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| STK3-ZHX2-20-RERE | 20 (40 μL) | 200 μL |
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| STK3-ZHX2-20-REOR | 20 (40 μL) | 200 μL |
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| STK3-ZHX2-20-REGO | 20 (40 μL) | 200 μL |
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| STK3-ZHX2-20-REGR | 20 (40 μL) | 200 μL |
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| STK3-ZHX2-20-REAQ | 20 (40 μL) | 200 μL |
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| STK3-ZHX2-20-ORRE | 20 (40 μL) | 200 μL |
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| STK3-ZHX2-20-OROR | 20 (40 μL) | 200 μL |
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| STK3-ZHX2-20-ORGO | 20 (40 μL) | 200 μL |
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| STK3-ZHX2-20-ORAQ | 20 (40 μL) | 200 μL |
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| STK3-ZHX2-20-GORE | 20 (40 μL) | 200 μL |
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| STK3-ZHX2-20-GOOR | 20 (40 μL) | 200 μL |
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| STK3-ZHX2-20-GOGO | 20 (40 μL) | 200 μL |
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| STK3-ZHX2-20-GOGR | 20 (40 μL) | 200 μL |
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| STK3-ZHX2-20-GOAQ | 20 (40 μL) | 200 μL |
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| STK3-ZHX2-20-GRRE | 20 (40 μL) | 200 μL |
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| STK3-ZHX2-20-GROR | 20 (40 μL) | 200 μL |
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| STK3-ZHX2-20-GRGO | 20 (40 μL) | 200 μL |
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| STK3-ZHX2-20-GRGR | 20 (40 μL) | 200 μL |
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| STK3-ZHX2-20-GRAQ | 20 (40 μL) | 200 μL |
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| STK3-ZHX2-20-AQRE | 20 (40 μL) | 200 μL |
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| STK3-ZHX2-20-AQOR | 20 (40 μL) | 200 μL |
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| STK3-ZHX2-20-AQGO | 20 (40 μL) | 200 μL |
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| STK3-ZHX2-20-AQGR | 20 (40 μL) | 200 μL |
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| STK3-ZHX2-20-AQAQ | 20 (40 μL) | 200 μL |
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STK3 Gene Summary
This gene encodes a serine/threonine protein kinase activated by proapoptotic molecules indicating the encoded protein functions as a growth suppressor. Cleavage of the protein product by caspase removes the inhibitory C-terminal portion. The N-terminal portion is transported to the nucleus where it homodimerizes to form the active kinase which promotes the condensation of chromatin during apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
Gene Name: Serine/threonine Kinase 3
Chromosome: CHR8: 99466860 -99837909
Locus: 8q22.2
ZHX2 Gene Summary
The members of the zinc fingers and homeoboxes gene family are nuclear homodimeric transcriptional repressors that interact with the A subunit of nuclear factor-Y (NF-YA) and contain two C2H2-type zinc fingers and five homeobox DNA-binding domains. This gene encodes member 2 of this gene family. In addition to forming homodimers, this protein heterodimerizes with member 1 of the zinc fingers and homeoboxes family. [provided by RefSeq, Jul 2008]
Gene Name: Zinc Fingers And Homeoboxes 2
Chromosome: CHR8: 123793900 -123986755
Locus: 8q24.13
Gene Diseases
The STK3 ZHX2 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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