STIP1-UBE2G1 Fusion FISH Probe
The STIP1-UBE2G1 Fusion FISH Probe is used to confirm a fusion of the STIP1 and UBE2G1 genes. The fusion of the STIP1 and UBE2G1 genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| STIP1-UBE2G1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| STIP1-UBE2G1-20-RERE | 20 (40 μL) | 200 μL |
|
|
| STIP1-UBE2G1-20-REOR | 20 (40 μL) | 200 μL |
|
|
| STIP1-UBE2G1-20-REGO | 20 (40 μL) | 200 μL |
|
|
| STIP1-UBE2G1-20-REGR | 20 (40 μL) | 200 μL |
|
|
| STIP1-UBE2G1-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| STIP1-UBE2G1-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| STIP1-UBE2G1-20-OROR | 20 (40 μL) | 200 μL |
|
|
| STIP1-UBE2G1-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| STIP1-UBE2G1-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| STIP1-UBE2G1-20-GORE | 20 (40 μL) | 200 μL |
|
|
| STIP1-UBE2G1-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| STIP1-UBE2G1-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| STIP1-UBE2G1-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| STIP1-UBE2G1-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| STIP1-UBE2G1-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| STIP1-UBE2G1-20-GROR | 20 (40 μL) | 200 μL |
|
|
| STIP1-UBE2G1-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| STIP1-UBE2G1-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| STIP1-UBE2G1-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| STIP1-UBE2G1-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| STIP1-UBE2G1-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| STIP1-UBE2G1-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| STIP1-UBE2G1-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| STIP1-UBE2G1-20-AQAQ | 20 (40 μL) | 200 μL |
|
UBE2G1 Gene Summary
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family and catalyzes the covalent attachment of ubiquitin to other proteins. The protein may be involved in degradation of muscle-specific proteins. [provided by RefSeq, Jul 2008]
Gene Name: Ubiquitin Conjugating Enzyme E2 G1
Chromosome: CHR17: 4172511 -4269969
Locus: 17p13.2
STIP1 Gene Summary
STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A; MIM 140550) and HSP90 (see HSP90AA1; MIM 140571) in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and Masison, 2005 [PubMed 16100115]).[supplied by OMIM, Jul 2009]
Gene Name: Stress Induced Phosphoprotein 1
Chromosome: CHR11: 63953586 -63972020
Locus: 11q13.1
Gene Diseases
The STIP1 UBE2G1 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|