STIM1-FITM2 Fusion FISH Probe
The STIM1-FITM2 Fusion FISH Probe is used to confirm a fusion of the STIM1 and FITM2 genes. The fusion of the STIM1 and FITM2 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| STIM1-FITM2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| STIM1-FITM2-20-RERE | 20 (40 μL) | 200 μL |
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| STIM1-FITM2-20-REOR | 20 (40 μL) | 200 μL |
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| STIM1-FITM2-20-REGO | 20 (40 μL) | 200 μL |
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| STIM1-FITM2-20-REGR | 20 (40 μL) | 200 μL |
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| STIM1-FITM2-20-REAQ | 20 (40 μL) | 200 μL |
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| STIM1-FITM2-20-ORRE | 20 (40 μL) | 200 μL |
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| STIM1-FITM2-20-OROR | 20 (40 μL) | 200 μL |
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| STIM1-FITM2-20-ORGO | 20 (40 μL) | 200 μL |
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| STIM1-FITM2-20-ORAQ | 20 (40 μL) | 200 μL |
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| STIM1-FITM2-20-GORE | 20 (40 μL) | 200 μL |
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| STIM1-FITM2-20-GOOR | 20 (40 μL) | 200 μL |
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| STIM1-FITM2-20-GOGO | 20 (40 μL) | 200 μL |
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| STIM1-FITM2-20-GOGR | 20 (40 μL) | 200 μL |
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| STIM1-FITM2-20-GOAQ | 20 (40 μL) | 200 μL |
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| STIM1-FITM2-20-GRRE | 20 (40 μL) | 200 μL |
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| STIM1-FITM2-20-GROR | 20 (40 μL) | 200 μL |
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| STIM1-FITM2-20-GRGO | 20 (40 μL) | 200 μL |
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| STIM1-FITM2-20-GRGR | 20 (40 μL) | 200 μL |
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| STIM1-FITM2-20-GRAQ | 20 (40 μL) | 200 μL |
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| STIM1-FITM2-20-AQRE | 20 (40 μL) | 200 μL |
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| STIM1-FITM2-20-AQOR | 20 (40 μL) | 200 μL |
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| STIM1-FITM2-20-AQGO | 20 (40 μL) | 200 μL |
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| STIM1-FITM2-20-AQGR | 20 (40 μL) | 200 μL |
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| STIM1-FITM2-20-AQAQ | 20 (40 μL) | 200 μL |
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STIM1 Gene Summary
This gene encodes a type 1 transmembrane protein that mediates Ca2+ influx after depletion of intracellular Ca2+ stores by gating of store-operated Ca2+ influx channels (SOCs). It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region, as well as early hematopoiesis, by mediating attachment to stromal cells. Mutations in this gene are associated with fatal classic Kaposi sarcoma, immunodeficiency due to defects in store-operated calcium entry (SOCE) in fibroblasts, ectodermal dysplasia and tubular aggregate myopathy. This gene is oriented in a head-to-tail configuration with the ribonucleotide reductase 1 gene (RRM1), with the 3' end of this gene situated 1.6 kb from the 5' end of the RRM1 gene. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2013]
Gene Name: Stromal Interaction Molecule 1
Chromosome: CHR11: 3876932 -4114440
Locus: 11p15.4
FITM2 Gene Summary
FIT2 belongs to an evolutionarily conserved family of proteins involved in fat storage (Kadereit et al., 2008 [PubMed 18160536]).[supplied by OMIM, May 2008]
Gene Name: Fat Storage Inducing Transmembrane Protein 2
Chromosome: CHR20: 42935196 -42939889
Locus: 20q13.12
Gene Diseases
The STIM1 FITM2 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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