STAU2-OSBPL2 Fusion FISH Probe
The STAU2-OSBPL2 Fusion FISH Probe is used to confirm a fusion of the STAU2 and OSBPL2 genes. The fusion of the STAU2 and OSBPL2 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| STAU2-OSBPL2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| STAU2-OSBPL2-20-RERE | 20 (40 μL) | 200 μL |
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| STAU2-OSBPL2-20-REOR | 20 (40 μL) | 200 μL |
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| STAU2-OSBPL2-20-REGO | 20 (40 μL) | 200 μL |
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| STAU2-OSBPL2-20-REGR | 20 (40 μL) | 200 μL |
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| STAU2-OSBPL2-20-REAQ | 20 (40 μL) | 200 μL |
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| STAU2-OSBPL2-20-ORRE | 20 (40 μL) | 200 μL |
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| STAU2-OSBPL2-20-OROR | 20 (40 μL) | 200 μL |
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| STAU2-OSBPL2-20-ORGO | 20 (40 μL) | 200 μL |
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| STAU2-OSBPL2-20-ORAQ | 20 (40 μL) | 200 μL |
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| STAU2-OSBPL2-20-GORE | 20 (40 μL) | 200 μL |
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| STAU2-OSBPL2-20-GOOR | 20 (40 μL) | 200 μL |
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| STAU2-OSBPL2-20-GOGO | 20 (40 μL) | 200 μL |
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| STAU2-OSBPL2-20-GOGR | 20 (40 μL) | 200 μL |
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| STAU2-OSBPL2-20-GOAQ | 20 (40 μL) | 200 μL |
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| STAU2-OSBPL2-20-GRRE | 20 (40 μL) | 200 μL |
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| STAU2-OSBPL2-20-GROR | 20 (40 μL) | 200 μL |
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| STAU2-OSBPL2-20-GRGO | 20 (40 μL) | 200 μL |
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| STAU2-OSBPL2-20-GRGR | 20 (40 μL) | 200 μL |
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| STAU2-OSBPL2-20-GRAQ | 20 (40 μL) | 200 μL |
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| STAU2-OSBPL2-20-AQRE | 20 (40 μL) | 200 μL |
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| STAU2-OSBPL2-20-AQOR | 20 (40 μL) | 200 μL |
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| STAU2-OSBPL2-20-AQGO | 20 (40 μL) | 200 μL |
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| STAU2-OSBPL2-20-AQGR | 20 (40 μL) | 200 μL |
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| STAU2-OSBPL2-20-AQAQ | 20 (40 μL) | 200 μL |
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OSBPL2 Gene Summary
This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although the encoded protein contains only the sterol-binding domain. In vitro studies have shown that the encoded protein can bind strongly to phosphatic acid and weakly to phosphatidylinositol 3-phosphate, but cannot bind to 25-hydroxycholesterol. The protein associates with the Golgi apparatus. Transcript variants encoding different isoforms have been described. [provided by RefSeq, Sep 2014]
Gene Name: Oxysterol Binding Protein Like 2
Chromosome: CHR20: 60813579 -60871269
Locus: 20q13.33
STAU2 Gene Summary
Staufen homolog 2 is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. Staufen homolog 2 shares 48.5% and 59.9% similarity with drosophila and human staufen, respectively. The exact function of Staufen homolog 2 is not known, but since it contains 3 copies of conserved dsRNA binding domain, it could be involved in double-stranded RNA binding events. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009]
Gene Name: Staufen Double-stranded RNA Binding Protein 2
Chromosome: CHR8: 74332603 -74659162
Locus: 8q21.11
Gene Diseases
The STAU2 OSBPL2 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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