STAU1-MAP1LC3A Fusion FISH Probe
The STAU1-MAP1LC3A Fusion FISH Probe is used to confirm a fusion of the STAU1 and MAP1LC3A genes. The fusion of the STAU1 and MAP1LC3A genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| STAU1-MAP1LC3A-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| STAU1-MAP1LC3A-20-RERE | 20 (40 μL) | 200 μL |
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| STAU1-MAP1LC3A-20-REOR | 20 (40 μL) | 200 μL |
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| STAU1-MAP1LC3A-20-REGO | 20 (40 μL) | 200 μL |
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| STAU1-MAP1LC3A-20-REGR | 20 (40 μL) | 200 μL |
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| STAU1-MAP1LC3A-20-REAQ | 20 (40 μL) | 200 μL |
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| STAU1-MAP1LC3A-20-ORRE | 20 (40 μL) | 200 μL |
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| STAU1-MAP1LC3A-20-OROR | 20 (40 μL) | 200 μL |
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| STAU1-MAP1LC3A-20-ORGO | 20 (40 μL) | 200 μL |
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| STAU1-MAP1LC3A-20-ORAQ | 20 (40 μL) | 200 μL |
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| STAU1-MAP1LC3A-20-GORE | 20 (40 μL) | 200 μL |
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| STAU1-MAP1LC3A-20-GOOR | 20 (40 μL) | 200 μL |
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| STAU1-MAP1LC3A-20-GOGO | 20 (40 μL) | 200 μL |
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| STAU1-MAP1LC3A-20-GOGR | 20 (40 μL) | 200 μL |
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| STAU1-MAP1LC3A-20-GOAQ | 20 (40 μL) | 200 μL |
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| STAU1-MAP1LC3A-20-GRRE | 20 (40 μL) | 200 μL |
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| STAU1-MAP1LC3A-20-GROR | 20 (40 μL) | 200 μL |
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| STAU1-MAP1LC3A-20-GRGO | 20 (40 μL) | 200 μL |
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| STAU1-MAP1LC3A-20-GRGR | 20 (40 μL) | 200 μL |
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| STAU1-MAP1LC3A-20-GRAQ | 20 (40 μL) | 200 μL |
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| STAU1-MAP1LC3A-20-AQRE | 20 (40 μL) | 200 μL |
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| STAU1-MAP1LC3A-20-AQOR | 20 (40 μL) | 200 μL |
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| STAU1-MAP1LC3A-20-AQGO | 20 (40 μL) | 200 μL |
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| STAU1-MAP1LC3A-20-AQGR | 20 (40 μL) | 200 μL |
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| STAU1-MAP1LC3A-20-AQAQ | 20 (40 μL) | 200 μL |
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STAU1 Gene Summary
Staufen is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. The human homologue of staufen encoded by STAU, in addition contains a microtubule- binding domain similar to that of microtubule-associated protein 1B, and binds tubulin. The STAU gene product has been shown to be present in the cytoplasm in association with the rough endoplasmic reticulum (RER), implicating this protein in the transport of mRNA via the microtubule network to the RER, the site of translation. Five transcript variants resulting from alternative splicing of STAU gene and encoding three isoforms have been described. Three of these variants encode the same isoform, however, differ in their 5'UTR. [provided by RefSeq, Jul 2008]
Gene Name: Staufen Double-stranded RNA Binding Protein 1
Chromosome: CHR20: 47729875 -47804904
Locus: 20q13.13
MAP1LC3A Gene Summary
MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. The protein encoded by this gene is one of the light chain subunits and can associate with either MAP1A or MAP1B. Two transcript variants encoding different isoforms have been found for this gene. The expression of variant 1 is suppressed in many tumor cell lines, suggesting that may be involved in carcinogenesis. [provided by RefSeq, Feb 2012]
Gene Name: Microtubule Associated Protein 1 Light Chain 3 Alpha
Chromosome: CHR20: 33134691 -33148149
Locus: 20q11.22
Gene Diseases
The STAU1 MAP1LC3A Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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