STAU1-CYP26B1 Fusion FISH Probe
The STAU1-CYP26B1 Fusion FISH Probe is used to confirm a fusion of the STAU1 and CYP26B1 genes. The fusion of the STAU1 and CYP26B1 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| STAU1-CYP26B1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| STAU1-CYP26B1-20-RERE | 20 (40 μL) | 200 μL |
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| STAU1-CYP26B1-20-REOR | 20 (40 μL) | 200 μL |
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| STAU1-CYP26B1-20-REGO | 20 (40 μL) | 200 μL |
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| STAU1-CYP26B1-20-REGR | 20 (40 μL) | 200 μL |
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| STAU1-CYP26B1-20-REAQ | 20 (40 μL) | 200 μL |
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| STAU1-CYP26B1-20-ORRE | 20 (40 μL) | 200 μL |
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| STAU1-CYP26B1-20-OROR | 20 (40 μL) | 200 μL |
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| STAU1-CYP26B1-20-ORGO | 20 (40 μL) | 200 μL |
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| STAU1-CYP26B1-20-ORAQ | 20 (40 μL) | 200 μL |
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| STAU1-CYP26B1-20-GORE | 20 (40 μL) | 200 μL |
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| STAU1-CYP26B1-20-GOOR | 20 (40 μL) | 200 μL |
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| STAU1-CYP26B1-20-GOGO | 20 (40 μL) | 200 μL |
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| STAU1-CYP26B1-20-GOGR | 20 (40 μL) | 200 μL |
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| STAU1-CYP26B1-20-GOAQ | 20 (40 μL) | 200 μL |
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| STAU1-CYP26B1-20-GRRE | 20 (40 μL) | 200 μL |
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| STAU1-CYP26B1-20-GROR | 20 (40 μL) | 200 μL |
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| STAU1-CYP26B1-20-GRGO | 20 (40 μL) | 200 μL |
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| STAU1-CYP26B1-20-GRGR | 20 (40 μL) | 200 μL |
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| STAU1-CYP26B1-20-GRAQ | 20 (40 μL) | 200 μL |
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| STAU1-CYP26B1-20-AQRE | 20 (40 μL) | 200 μL |
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| STAU1-CYP26B1-20-AQOR | 20 (40 μL) | 200 μL |
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| STAU1-CYP26B1-20-AQGO | 20 (40 μL) | 200 μL |
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| STAU1-CYP26B1-20-AQGR | 20 (40 μL) | 200 μL |
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| STAU1-CYP26B1-20-AQAQ | 20 (40 μL) | 200 μL |
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STAU1 Gene Summary
Staufen is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. The human homologue of staufen encoded by STAU, in addition contains a microtubule- binding domain similar to that of microtubule-associated protein 1B, and binds tubulin. The STAU gene product has been shown to be present in the cytoplasm in association with the rough endoplasmic reticulum (RER), implicating this protein in the transport of mRNA via the microtubule network to the RER, the site of translation. Five transcript variants resulting from alternative splicing of STAU gene and encoding three isoforms have been described. Three of these variants encode the same isoform, however, differ in their 5'UTR. [provided by RefSeq, Jul 2008]
Gene Name: Staufen Double-stranded RNA Binding Protein 1
Chromosome: CHR20: 47729875 -47804904
Locus: 20q13.13
CYP26B1 Gene Summary
This gene encodes a member of the cytochrome P450 superfamily. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein is localized to the endoplasmic reticulum, and functions as a critical regulator of all-trans retinoic acid levels by the specific inactivation of all-trans retinoic acid to hydroxylated forms. Mutations in this gene are associated with radiohumeral fusions and other skeletal and craniofacial anomalies, and increased levels of the encoded protein are associated with atherosclerotic lesions. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013]
Gene Name: Cytochrome P450 Family 26 Subfamily B Member 1
Chromosome: CHR2: 72356366 -72374963
Locus: 2p13.2
Gene Diseases
The STAU1 CYP26B1 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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