STARD4-ASTN2 Fusion FISH Probe
The STARD4-ASTN2 Fusion FISH Probe is used to confirm a fusion of the STARD4 and ASTN2 genes. The fusion of the STARD4 and ASTN2 genes has been associated with Pancreatic Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| STARD4-ASTN2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| STARD4-ASTN2-20-RERE | 20 (40 μL) | 200 μL |
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| STARD4-ASTN2-20-REOR | 20 (40 μL) | 200 μL |
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| STARD4-ASTN2-20-REGO | 20 (40 μL) | 200 μL |
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| STARD4-ASTN2-20-REGR | 20 (40 μL) | 200 μL |
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| STARD4-ASTN2-20-REAQ | 20 (40 μL) | 200 μL |
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| STARD4-ASTN2-20-ORRE | 20 (40 μL) | 200 μL |
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| STARD4-ASTN2-20-OROR | 20 (40 μL) | 200 μL |
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| STARD4-ASTN2-20-ORGO | 20 (40 μL) | 200 μL |
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| STARD4-ASTN2-20-ORAQ | 20 (40 μL) | 200 μL |
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| STARD4-ASTN2-20-GORE | 20 (40 μL) | 200 μL |
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| STARD4-ASTN2-20-GOOR | 20 (40 μL) | 200 μL |
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| STARD4-ASTN2-20-GOGO | 20 (40 μL) | 200 μL |
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| STARD4-ASTN2-20-GOGR | 20 (40 μL) | 200 μL |
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| STARD4-ASTN2-20-GOAQ | 20 (40 μL) | 200 μL |
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| STARD4-ASTN2-20-GRRE | 20 (40 μL) | 200 μL |
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| STARD4-ASTN2-20-GROR | 20 (40 μL) | 200 μL |
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| STARD4-ASTN2-20-GRGO | 20 (40 μL) | 200 μL |
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| STARD4-ASTN2-20-GRGR | 20 (40 μL) | 200 μL |
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| STARD4-ASTN2-20-GRAQ | 20 (40 μL) | 200 μL |
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| STARD4-ASTN2-20-AQRE | 20 (40 μL) | 200 μL |
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| STARD4-ASTN2-20-AQOR | 20 (40 μL) | 200 μL |
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| STARD4-ASTN2-20-AQGO | 20 (40 μL) | 200 μL |
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| STARD4-ASTN2-20-AQGR | 20 (40 μL) | 200 μL |
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| STARD4-ASTN2-20-AQAQ | 20 (40 μL) | 200 μL |
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ASTN2 Gene Summary
This gene encodes a protein that is expressed in the brain and may function in neuronal migration, based on functional studies of the related astrotactin 1 gene in human and mouse. A deletion at this locus has been associated with schizophrenia. Multiple transcript variants encoding different proteins have been found for this locus. [provided by RefSeq, May 2010]
Gene Name: Astrotactin 2
Chromosome: CHR9: 119187503 -120177317
Locus: 9q33.1
STARD4 Gene Summary
Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e.g., SREBP1; MIM 184756) and by liver X receptors (e.g., LXRA; MIM 602423). Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake. Sterol transport is mediated by vesicles or by soluble protein carriers, such as steroidogenic acute regulatory protein (STAR; MIM 600617). STAR is homologous to a family of proteins containing a 200- to 210-amino acid STAR-related lipid transfer (START) domain, including STARD4 (Soccio et al., 2002 [PubMed 12011452]).[supplied by OMIM, Mar 2008]
Gene Name: StAR Related Lipid Transfer Domain Containing 4
Chromosome: CHR5: 110834021 -110848157
Locus: 5q22.1
Gene Diseases
The STARD4 ASTN2 Fusion has been associated with the following diseases:
| Disease Name |
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| Pancreatic Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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