STARD3-GSDMB Fusion FISH Probe
The STARD3-GSDMB Fusion FISH Probe is used to confirm a fusion of the STARD3 and GSDMB genes. The fusion of the STARD3 and GSDMB genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| STARD3-GSDMB-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| STARD3-GSDMB-20-RERE | 20 (40 μL) | 200 μL |
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| STARD3-GSDMB-20-REOR | 20 (40 μL) | 200 μL |
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| STARD3-GSDMB-20-REGO | 20 (40 μL) | 200 μL |
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| STARD3-GSDMB-20-REGR | 20 (40 μL) | 200 μL |
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| STARD3-GSDMB-20-REAQ | 20 (40 μL) | 200 μL |
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| STARD3-GSDMB-20-ORRE | 20 (40 μL) | 200 μL |
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| STARD3-GSDMB-20-OROR | 20 (40 μL) | 200 μL |
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| STARD3-GSDMB-20-ORGO | 20 (40 μL) | 200 μL |
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| STARD3-GSDMB-20-ORAQ | 20 (40 μL) | 200 μL |
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| STARD3-GSDMB-20-GORE | 20 (40 μL) | 200 μL |
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| STARD3-GSDMB-20-GOOR | 20 (40 μL) | 200 μL |
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| STARD3-GSDMB-20-GOGO | 20 (40 μL) | 200 μL |
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| STARD3-GSDMB-20-GOGR | 20 (40 μL) | 200 μL |
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| STARD3-GSDMB-20-GOAQ | 20 (40 μL) | 200 μL |
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| STARD3-GSDMB-20-GRRE | 20 (40 μL) | 200 μL |
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| STARD3-GSDMB-20-GROR | 20 (40 μL) | 200 μL |
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| STARD3-GSDMB-20-GRGO | 20 (40 μL) | 200 μL |
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| STARD3-GSDMB-20-GRGR | 20 (40 μL) | 200 μL |
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| STARD3-GSDMB-20-GRAQ | 20 (40 μL) | 200 μL |
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| STARD3-GSDMB-20-AQRE | 20 (40 μL) | 200 μL |
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| STARD3-GSDMB-20-AQOR | 20 (40 μL) | 200 μL |
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| STARD3-GSDMB-20-AQGO | 20 (40 μL) | 200 μL |
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| STARD3-GSDMB-20-AQGR | 20 (40 μL) | 200 μL |
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| STARD3-GSDMB-20-AQAQ | 20 (40 μL) | 200 μL |
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STARD3 Gene Summary
This gene encodes a member of a subfamily of lipid trafficking proteins that are characterized by a C-terminal steroidogenic acute regulatory domain and an N-terminal metastatic lymph node 64 domain. The encoded protein localizes to the membranes of late endosomes and may be involved in exporting cholesterol. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Oct 2009]
Gene Name: StAR Related Lipid Transfer Domain Containing 3
Chromosome: CHR17: 37793332 -37820454
Locus: 17q12
GSDMB Gene Summary
This gene encodes a member of the gasdermin-domain containing protein family. Other gasdermin-family genes are implicated in the regulation of apoptosis in epithelial cells, and are linked to cancer. Alternative splicing and the use of alternative promoters results in multiple transcript variants. Additional variants have been described, but they are candidates for nonsense-mediated mRNA decay (NMD) and are unlikely to be protein-coding. [provided by RefSeq, Nov 2016]
Gene Name: Gasdermin B
Chromosome: CHR17: 38060847 -38074903
Locus: 17q21.1
Gene Diseases
The STARD3 GSDMB Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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