STAG2-GRIA3 Fusion FISH Probe
The STAG2-GRIA3 Fusion FISH Probe is used to confirm a fusion of the STAG2 and GRIA3 genes. The fusion of the STAG2 and GRIA3 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| STAG2-GRIA3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| STAG2-GRIA3-20-RERE | 20 (40 μL) | 200 μL |
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| STAG2-GRIA3-20-REOR | 20 (40 μL) | 200 μL |
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| STAG2-GRIA3-20-REGO | 20 (40 μL) | 200 μL |
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| STAG2-GRIA3-20-REGR | 20 (40 μL) | 200 μL |
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| STAG2-GRIA3-20-REAQ | 20 (40 μL) | 200 μL |
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| STAG2-GRIA3-20-ORRE | 20 (40 μL) | 200 μL |
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| STAG2-GRIA3-20-OROR | 20 (40 μL) | 200 μL |
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| STAG2-GRIA3-20-ORGO | 20 (40 μL) | 200 μL |
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| STAG2-GRIA3-20-ORAQ | 20 (40 μL) | 200 μL |
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| STAG2-GRIA3-20-GORE | 20 (40 μL) | 200 μL |
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| STAG2-GRIA3-20-GOOR | 20 (40 μL) | 200 μL |
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| STAG2-GRIA3-20-GOGO | 20 (40 μL) | 200 μL |
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| STAG2-GRIA3-20-GOGR | 20 (40 μL) | 200 μL |
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| STAG2-GRIA3-20-GOAQ | 20 (40 μL) | 200 μL |
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| STAG2-GRIA3-20-GRRE | 20 (40 μL) | 200 μL |
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| STAG2-GRIA3-20-GROR | 20 (40 μL) | 200 μL |
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| STAG2-GRIA3-20-GRGO | 20 (40 μL) | 200 μL |
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| STAG2-GRIA3-20-GRGR | 20 (40 μL) | 200 μL |
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| STAG2-GRIA3-20-GRAQ | 20 (40 μL) | 200 μL |
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| STAG2-GRIA3-20-AQRE | 20 (40 μL) | 200 μL |
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| STAG2-GRIA3-20-AQOR | 20 (40 μL) | 200 μL |
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| STAG2-GRIA3-20-AQGO | 20 (40 μL) | 200 μL |
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| STAG2-GRIA3-20-AQGR | 20 (40 μL) | 200 μL |
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| STAG2-GRIA3-20-AQAQ | 20 (40 μL) | 200 μL |
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GRIA3 Gene Summary
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing at this locus results in different isoforms, which may vary in their signal transduction properties. [provided by RefSeq, Jul 2008]
Gene Name: Glutamate Ionotropic Receptor AMPA Type Subunit 3
Chromosome: CHRX: 122318095 -122624766
Locus: Xq25
STAG2 Gene Summary
The protein encoded by this gene is a subunit of the cohesin complex, which regulates the separation of sister chromatids during cell division. Targeted inactivation of this gene results in chromatid cohesion defects and aneuploidy, suggesting that genetic disruption of cohesin is a cause of aneuploidy in human cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]
Gene Name: Stromal Antigen 2
Chromosome: CHRX: 123094474 -123236505
Locus: Xq25
Gene Diseases
The STAG2 GRIA3 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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