STAG2-AMMECR1 Fusion FISH Probe
The STAG2-AMMECR1 Fusion FISH Probe is used to confirm a fusion of the STAG2 and AMMECR1 genes. The fusion of the STAG2 and AMMECR1 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| STAG2-AMMECR1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| STAG2-AMMECR1-20-RERE | 20 (40 μL) | 200 μL |
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| STAG2-AMMECR1-20-REOR | 20 (40 μL) | 200 μL |
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| STAG2-AMMECR1-20-REGO | 20 (40 μL) | 200 μL |
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| STAG2-AMMECR1-20-REGR | 20 (40 μL) | 200 μL |
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| STAG2-AMMECR1-20-REAQ | 20 (40 μL) | 200 μL |
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| STAG2-AMMECR1-20-ORRE | 20 (40 μL) | 200 μL |
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| STAG2-AMMECR1-20-OROR | 20 (40 μL) | 200 μL |
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| STAG2-AMMECR1-20-ORGO | 20 (40 μL) | 200 μL |
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| STAG2-AMMECR1-20-ORAQ | 20 (40 μL) | 200 μL |
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| STAG2-AMMECR1-20-GORE | 20 (40 μL) | 200 μL |
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| STAG2-AMMECR1-20-GOOR | 20 (40 μL) | 200 μL |
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| STAG2-AMMECR1-20-GOGO | 20 (40 μL) | 200 μL |
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| STAG2-AMMECR1-20-GOGR | 20 (40 μL) | 200 μL |
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| STAG2-AMMECR1-20-GOAQ | 20 (40 μL) | 200 μL |
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| STAG2-AMMECR1-20-GRRE | 20 (40 μL) | 200 μL |
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| STAG2-AMMECR1-20-GROR | 20 (40 μL) | 200 μL |
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| STAG2-AMMECR1-20-GRGO | 20 (40 μL) | 200 μL |
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| STAG2-AMMECR1-20-GRGR | 20 (40 μL) | 200 μL |
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| STAG2-AMMECR1-20-GRAQ | 20 (40 μL) | 200 μL |
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| STAG2-AMMECR1-20-AQRE | 20 (40 μL) | 200 μL |
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| STAG2-AMMECR1-20-AQOR | 20 (40 μL) | 200 μL |
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| STAG2-AMMECR1-20-AQGO | 20 (40 μL) | 200 μL |
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| STAG2-AMMECR1-20-AQGR | 20 (40 μL) | 200 μL |
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| STAG2-AMMECR1-20-AQAQ | 20 (40 μL) | 200 μL |
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AMMECR1 Gene Summary
The exact function of this gene is not known, however, submicroscopic deletion of the X chromosome including this gene, COL4A5, and FACL4 genes, result in a contiguous gene deletion syndrome, the AMME complex (Alport syndrome, mental retardation, midface hypoplasia, and elliptocytosis). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]
Gene Name: Alport Syndrome, Mental Retardation, Midface Hypoplasia And Elliptocytosis Chromosomal Region Gene 1
Chromosome: CHRX: 109437413 -109683461
Locus: Xq23
STAG2 Gene Summary
The protein encoded by this gene is a subunit of the cohesin complex, which regulates the separation of sister chromatids during cell division. Targeted inactivation of this gene results in chromatid cohesion defects and aneuploidy, suggesting that genetic disruption of cohesin is a cause of aneuploidy in human cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]
Gene Name: Stromal Antigen 2
Chromosome: CHRX: 123094474 -123236505
Locus: Xq25
Gene Diseases
The STAG2 AMMECR1 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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