ST7L-AP2A2 Fusion FISH Probe
The ST7L-AP2A2 Fusion FISH Probe is used to confirm a fusion of the ST7L and AP2A2 genes. The fusion of the ST7L and AP2A2 genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ST7L-AP2A2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ST7L-AP2A2-20-RERE | 20 (40 μL) | 200 μL |
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| ST7L-AP2A2-20-REOR | 20 (40 μL) | 200 μL |
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| ST7L-AP2A2-20-REGO | 20 (40 μL) | 200 μL |
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| ST7L-AP2A2-20-REGR | 20 (40 μL) | 200 μL |
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| ST7L-AP2A2-20-REAQ | 20 (40 μL) | 200 μL |
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| ST7L-AP2A2-20-ORRE | 20 (40 μL) | 200 μL |
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| ST7L-AP2A2-20-OROR | 20 (40 μL) | 200 μL |
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| ST7L-AP2A2-20-ORGO | 20 (40 μL) | 200 μL |
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| ST7L-AP2A2-20-ORAQ | 20 (40 μL) | 200 μL |
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| ST7L-AP2A2-20-GORE | 20 (40 μL) | 200 μL |
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| ST7L-AP2A2-20-GOOR | 20 (40 μL) | 200 μL |
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| ST7L-AP2A2-20-GOGO | 20 (40 μL) | 200 μL |
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| ST7L-AP2A2-20-GOGR | 20 (40 μL) | 200 μL |
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| ST7L-AP2A2-20-GOAQ | 20 (40 μL) | 200 μL |
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| ST7L-AP2A2-20-GRRE | 20 (40 μL) | 200 μL |
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| ST7L-AP2A2-20-GROR | 20 (40 μL) | 200 μL |
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| ST7L-AP2A2-20-GRGO | 20 (40 μL) | 200 μL |
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| ST7L-AP2A2-20-GRGR | 20 (40 μL) | 200 μL |
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| ST7L-AP2A2-20-GRAQ | 20 (40 μL) | 200 μL |
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| ST7L-AP2A2-20-AQRE | 20 (40 μL) | 200 μL |
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| ST7L-AP2A2-20-AQOR | 20 (40 μL) | 200 μL |
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| ST7L-AP2A2-20-AQGO | 20 (40 μL) | 200 μL |
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| ST7L-AP2A2-20-AQGR | 20 (40 μL) | 200 μL |
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| ST7L-AP2A2-20-AQAQ | 20 (40 μL) | 200 μL |
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AP2A2 Gene Summary
The protein encoded by this gene is a subunit of the AP-2 adaptor protein complex, which is involved in linking lipid and protein membrane components with the clathrin lattice. This interaction supports the formation of clathrin-coated vesicles, and the encoded subunit aids in the process by binding polyphosphoinositide-containing lipids in the cell membrane. [provided by RefSeq, Nov 2016]
Gene Name: Adaptor Related Protein Complex 2 Alpha 2 Subunit
Chromosome: CHR11: 925808 -1012245
Locus: 11p15.5
ST7L Gene Summary
This gene was identified by its similarity to the ST7 tumor suppressor gene found in the chromosome 7q31 region. This gene is clustered in a tail-to-tail manner with the WNT2B gene in a chromosomal region known to be deleted and rearranged in a variety of cancers. Several transcript variants encoding many different isoforms have been described, but some have not been fully characterized. [provided by RefSeq, Feb 2011]
Gene Name: Suppression Of Tumorigenicity 7 Like
Chromosome: CHR1: 113066140 -113162040
Locus: 1p13.2
Gene Diseases
The ST7L AP2A2 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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