ST7-COG5 Fusion FISH Probe
The ST7-COG5 Fusion FISH Probe is used to confirm a fusion of the ST7 and COG5 genes. The fusion of the ST7 and COG5 genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ST7-COG5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ST7-COG5-20-RERE | 20 (40 μL) | 200 μL |
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| ST7-COG5-20-REOR | 20 (40 μL) | 200 μL |
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| ST7-COG5-20-REGO | 20 (40 μL) | 200 μL |
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| ST7-COG5-20-REGR | 20 (40 μL) | 200 μL |
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| ST7-COG5-20-REAQ | 20 (40 μL) | 200 μL |
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| ST7-COG5-20-ORRE | 20 (40 μL) | 200 μL |
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| ST7-COG5-20-OROR | 20 (40 μL) | 200 μL |
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| ST7-COG5-20-ORGO | 20 (40 μL) | 200 μL |
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| ST7-COG5-20-ORAQ | 20 (40 μL) | 200 μL |
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| ST7-COG5-20-GORE | 20 (40 μL) | 200 μL |
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| ST7-COG5-20-GOOR | 20 (40 μL) | 200 μL |
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| ST7-COG5-20-GOGO | 20 (40 μL) | 200 μL |
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| ST7-COG5-20-GOGR | 20 (40 μL) | 200 μL |
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| ST7-COG5-20-GOAQ | 20 (40 μL) | 200 μL |
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| ST7-COG5-20-GRRE | 20 (40 μL) | 200 μL |
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| ST7-COG5-20-GROR | 20 (40 μL) | 200 μL |
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| ST7-COG5-20-GRGO | 20 (40 μL) | 200 μL |
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| ST7-COG5-20-GRGR | 20 (40 μL) | 200 μL |
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| ST7-COG5-20-GRAQ | 20 (40 μL) | 200 μL |
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| ST7-COG5-20-AQRE | 20 (40 μL) | 200 μL |
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| ST7-COG5-20-AQOR | 20 (40 μL) | 200 μL |
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| ST7-COG5-20-AQGO | 20 (40 μL) | 200 μL |
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| ST7-COG5-20-AQGR | 20 (40 μL) | 200 μL |
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| ST7-COG5-20-AQAQ | 20 (40 μL) | 200 μL |
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ST7 Gene Summary
The gene for this product maps to a region on chromosome 7 identified as an autism-susceptibility locus. Mutation screening of the entire coding region in autistic individuals failed to identify phenotype-specific variants, suggesting that coding mutations for this gene are unlikely to be involved in the etiology of autism. The function of this gene product has not been determined. Transcript variants encoding different isoforms of this protein have been described. [provided by RefSeq, Jul 2008]
Gene Name: Suppression Of Tumorigenicity 7
Chromosome: CHR7: 116593380 -116870075
Locus: 7q31.2
COG5 Gene Summary
The protein encoded by this gene is one of eight proteins (Cog1-8) which form a Golgi-localized complex (COG) required for normal Golgi morphology and function. The encoded protein is organized with conserved oligomeric Golgi complex components 6, 7 and 8 into a sub-complex referred to as lobe B. Alternative splicing results in multiple transcript variants. Mutations in this gene result in congenital disorder of glycosylation type 2I.[provided by RefSeq, Jan 2011]
Gene Name: Component Of Oligomeric Golgi Complex 5
Chromosome: CHR7: 106842188 -107204959
Locus: 7q22.3
Gene Diseases
The ST7 COG5 Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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