ST7-CAV1 Fusion FISH Probe
The ST7-CAV1 Fusion FISH Probe is used to confirm a fusion of the ST7 and CAV1 genes. The fusion of the ST7 and CAV1 genes has been associated with Glioblastoma Multiforme. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ST7-CAV1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ST7-CAV1-20-RERE | 20 (40 μL) | 200 μL |
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| ST7-CAV1-20-REOR | 20 (40 μL) | 200 μL |
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| ST7-CAV1-20-REGO | 20 (40 μL) | 200 μL |
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| ST7-CAV1-20-REGR | 20 (40 μL) | 200 μL |
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| ST7-CAV1-20-REAQ | 20 (40 μL) | 200 μL |
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| ST7-CAV1-20-ORRE | 20 (40 μL) | 200 μL |
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| ST7-CAV1-20-OROR | 20 (40 μL) | 200 μL |
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| ST7-CAV1-20-ORGO | 20 (40 μL) | 200 μL |
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| ST7-CAV1-20-ORAQ | 20 (40 μL) | 200 μL |
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| ST7-CAV1-20-GORE | 20 (40 μL) | 200 μL |
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| ST7-CAV1-20-GOOR | 20 (40 μL) | 200 μL |
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| ST7-CAV1-20-GOGO | 20 (40 μL) | 200 μL |
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| ST7-CAV1-20-GOGR | 20 (40 μL) | 200 μL |
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| ST7-CAV1-20-GOAQ | 20 (40 μL) | 200 μL |
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| ST7-CAV1-20-GRRE | 20 (40 μL) | 200 μL |
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| ST7-CAV1-20-GROR | 20 (40 μL) | 200 μL |
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| ST7-CAV1-20-GRGO | 20 (40 μL) | 200 μL |
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| ST7-CAV1-20-GRGR | 20 (40 μL) | 200 μL |
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| ST7-CAV1-20-GRAQ | 20 (40 μL) | 200 μL |
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| ST7-CAV1-20-AQRE | 20 (40 μL) | 200 μL |
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| ST7-CAV1-20-AQOR | 20 (40 μL) | 200 μL |
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| ST7-CAV1-20-AQGO | 20 (40 μL) | 200 μL |
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| ST7-CAV1-20-AQGR | 20 (40 μL) | 200 μL |
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| ST7-CAV1-20-AQAQ | 20 (40 μL) | 200 μL |
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CAV1 Gene Summary
The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.[provided by RefSeq, Mar 2010]
Gene Name: Caveolin 1
Chromosome: CHR7: 116164838 -116201239
Locus: 7q31.2
ST7 Gene Summary
The gene for this product maps to a region on chromosome 7 identified as an autism-susceptibility locus. Mutation screening of the entire coding region in autistic individuals failed to identify phenotype-specific variants, suggesting that coding mutations for this gene are unlikely to be involved in the etiology of autism. The function of this gene product has not been determined. Transcript variants encoding different isoforms of this protein have been described. [provided by RefSeq, Jul 2008]
Gene Name: Suppression Of Tumorigenicity 7
Chromosome: CHR7: 116593380 -116870075
Locus: 7q31.2
Gene Diseases
The ST7 CAV1 Fusion has been associated with the following diseases:
| Disease Name |
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| Glioblastoma Multiforme |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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