ST3GAL3-TGFBR3 Fusion FISH Probe
The ST3GAL3-TGFBR3 Fusion FISH Probe is used to confirm a fusion of the ST3GAL3 and TGFBR3 genes. The fusion of the ST3GAL3 and TGFBR3 genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ST3GAL3-TGFBR3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ST3GAL3-TGFBR3-20-RERE | 20 (40 μL) | 200 μL |
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| ST3GAL3-TGFBR3-20-REOR | 20 (40 μL) | 200 μL |
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| ST3GAL3-TGFBR3-20-REGO | 20 (40 μL) | 200 μL |
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| ST3GAL3-TGFBR3-20-REGR | 20 (40 μL) | 200 μL |
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| ST3GAL3-TGFBR3-20-REAQ | 20 (40 μL) | 200 μL |
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| ST3GAL3-TGFBR3-20-ORRE | 20 (40 μL) | 200 μL |
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| ST3GAL3-TGFBR3-20-OROR | 20 (40 μL) | 200 μL |
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| ST3GAL3-TGFBR3-20-ORGO | 20 (40 μL) | 200 μL |
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| ST3GAL3-TGFBR3-20-ORAQ | 20 (40 μL) | 200 μL |
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| ST3GAL3-TGFBR3-20-GORE | 20 (40 μL) | 200 μL |
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| ST3GAL3-TGFBR3-20-GOOR | 20 (40 μL) | 200 μL |
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| ST3GAL3-TGFBR3-20-GOGO | 20 (40 μL) | 200 μL |
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| ST3GAL3-TGFBR3-20-GOGR | 20 (40 μL) | 200 μL |
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| ST3GAL3-TGFBR3-20-GOAQ | 20 (40 μL) | 200 μL |
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| ST3GAL3-TGFBR3-20-GRRE | 20 (40 μL) | 200 μL |
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| ST3GAL3-TGFBR3-20-GROR | 20 (40 μL) | 200 μL |
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| ST3GAL3-TGFBR3-20-GRGO | 20 (40 μL) | 200 μL |
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| ST3GAL3-TGFBR3-20-GRGR | 20 (40 μL) | 200 μL |
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| ST3GAL3-TGFBR3-20-GRAQ | 20 (40 μL) | 200 μL |
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| ST3GAL3-TGFBR3-20-AQRE | 20 (40 μL) | 200 μL |
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| ST3GAL3-TGFBR3-20-AQOR | 20 (40 μL) | 200 μL |
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| ST3GAL3-TGFBR3-20-AQGO | 20 (40 μL) | 200 μL |
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| ST3GAL3-TGFBR3-20-AQGR | 20 (40 μL) | 200 μL |
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| ST3GAL3-TGFBR3-20-AQAQ | 20 (40 μL) | 200 μL |
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ST3GAL3 Gene Summary
The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein is normally found in the Golgi apparatus but can be proteolytically processed to a soluble form. This protein is a member of glycosyltransferase family 29. Mutations in this gene have been associated with a form of autosomal recessive nonsymdromic cognitive disability as well as infantile epileptic encephalopathy. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2017]
Gene Name: ST3 Beta-galactoside Alpha-2,3-sialyltransferase 3
Chromosome: CHR1: 44173217 -44396831
Locus: 1p34.1
TGFBR3 Gene Summary
This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.[provided by RefSeq, Sep 2010]
Gene Name: Transforming Growth Factor Beta Receptor 3
Chromosome: CHR1: 92145899 -92371559
Locus: 1p22.1
Gene Diseases
The ST3GAL3 TGFBR3 Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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