ST3GAL1-COL22A1 Fusion FISH Probe
The ST3GAL1-COL22A1 Fusion FISH Probe is used to confirm a fusion of the ST3GAL1 and COL22A1 genes. The fusion of the ST3GAL1 and COL22A1 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ST3GAL1-COL22A1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ST3GAL1-COL22A1-20-RERE | 20 (40 μL) | 200 μL |
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| ST3GAL1-COL22A1-20-REOR | 20 (40 μL) | 200 μL |
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| ST3GAL1-COL22A1-20-REGO | 20 (40 μL) | 200 μL |
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| ST3GAL1-COL22A1-20-REGR | 20 (40 μL) | 200 μL |
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| ST3GAL1-COL22A1-20-REAQ | 20 (40 μL) | 200 μL |
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| ST3GAL1-COL22A1-20-ORRE | 20 (40 μL) | 200 μL |
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| ST3GAL1-COL22A1-20-OROR | 20 (40 μL) | 200 μL |
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| ST3GAL1-COL22A1-20-ORGO | 20 (40 μL) | 200 μL |
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| ST3GAL1-COL22A1-20-ORAQ | 20 (40 μL) | 200 μL |
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| ST3GAL1-COL22A1-20-GORE | 20 (40 μL) | 200 μL |
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| ST3GAL1-COL22A1-20-GOOR | 20 (40 μL) | 200 μL |
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| ST3GAL1-COL22A1-20-GOGO | 20 (40 μL) | 200 μL |
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| ST3GAL1-COL22A1-20-GOGR | 20 (40 μL) | 200 μL |
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| ST3GAL1-COL22A1-20-GOAQ | 20 (40 μL) | 200 μL |
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| ST3GAL1-COL22A1-20-GRRE | 20 (40 μL) | 200 μL |
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| ST3GAL1-COL22A1-20-GROR | 20 (40 μL) | 200 μL |
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| ST3GAL1-COL22A1-20-GRGO | 20 (40 μL) | 200 μL |
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| ST3GAL1-COL22A1-20-GRGR | 20 (40 μL) | 200 μL |
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| ST3GAL1-COL22A1-20-GRAQ | 20 (40 μL) | 200 μL |
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| ST3GAL1-COL22A1-20-AQRE | 20 (40 μL) | 200 μL |
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| ST3GAL1-COL22A1-20-AQOR | 20 (40 μL) | 200 μL |
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| ST3GAL1-COL22A1-20-AQGO | 20 (40 μL) | 200 μL |
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| ST3GAL1-COL22A1-20-AQGR | 20 (40 μL) | 200 μL |
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| ST3GAL1-COL22A1-20-AQAQ | 20 (40 μL) | 200 μL |
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ST3GAL1 Gene Summary
The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein is normally found in the Golgi but can be proteolytically processed to a soluble form. Correct glycosylation of the encoded protein may be critical to its sialyltransferase activity. This protein, which is a member of glycosyltransferase family 29, can use the same acceptor substrates as does sialyltransferase 4B. Two transcript variants encoding the same protein have been found for this gene. Other transcript variants may exist, but have not been fully characterized yet. [provided by RefSeq, Jul 2008]
Gene Name: ST3 Beta-galactoside Alpha-2,3-sialyltransferase 1
Chromosome: CHR8: 134467090 -134584183
Locus: 8q24.22
COL22A1 Gene Summary
This gene encodes member of the collagen family which is thought to contribute to the stabilization of myotendinous junctions and strengthen skeletal muscle attachments during contractile activity. It belongs to the fibril-associated collagens with interrupted triple helix (FACIT) subset of the collagen superfamily, which associate with collagen fibers through their C-terminal collagenous domains and mediate protein-protein interactions through their N-terminal noncollagenous domains. The encoded protein is deposited in the basement membrane zone of the myotendinous junction which is present only at the tissue junctions of muscles, tendons, the heart, articular cartilage, and skin. A knockdown of the orthologous zebrafish gene induces a muscular dystrophy by disruption of the myotendinous junction. [provided by RefSeq, May 2017]
Gene Name: Collagen Type XXII Alpha 1 Chain
Chromosome: CHR8: 139600477 -139926236
Locus: 8q24.23-q24.3
Gene Diseases
The ST3GAL1 COL22A1 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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