SSR1-FARS2 Fusion FISH Probe
The SSR1-FARS2 Fusion FISH Probe is used to confirm a fusion of the SSR1 and FARS2 genes. The fusion of the SSR1 and FARS2 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SSR1-FARS2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SSR1-FARS2-20-RERE | 20 (40 μL) | 200 μL |
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| SSR1-FARS2-20-REOR | 20 (40 μL) | 200 μL |
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| SSR1-FARS2-20-REGO | 20 (40 μL) | 200 μL |
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| SSR1-FARS2-20-REGR | 20 (40 μL) | 200 μL |
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| SSR1-FARS2-20-REAQ | 20 (40 μL) | 200 μL |
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| SSR1-FARS2-20-ORRE | 20 (40 μL) | 200 μL |
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| SSR1-FARS2-20-OROR | 20 (40 μL) | 200 μL |
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| SSR1-FARS2-20-ORGO | 20 (40 μL) | 200 μL |
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| SSR1-FARS2-20-ORAQ | 20 (40 μL) | 200 μL |
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| SSR1-FARS2-20-GORE | 20 (40 μL) | 200 μL |
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| SSR1-FARS2-20-GOOR | 20 (40 μL) | 200 μL |
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| SSR1-FARS2-20-GOGO | 20 (40 μL) | 200 μL |
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| SSR1-FARS2-20-GOGR | 20 (40 μL) | 200 μL |
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| SSR1-FARS2-20-GOAQ | 20 (40 μL) | 200 μL |
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| SSR1-FARS2-20-GRRE | 20 (40 μL) | 200 μL |
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| SSR1-FARS2-20-GROR | 20 (40 μL) | 200 μL |
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| SSR1-FARS2-20-GRGO | 20 (40 μL) | 200 μL |
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| SSR1-FARS2-20-GRGR | 20 (40 μL) | 200 μL |
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| SSR1-FARS2-20-GRAQ | 20 (40 μL) | 200 μL |
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| SSR1-FARS2-20-AQRE | 20 (40 μL) | 200 μL |
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| SSR1-FARS2-20-AQOR | 20 (40 μL) | 200 μL |
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| SSR1-FARS2-20-AQGO | 20 (40 μL) | 200 μL |
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| SSR1-FARS2-20-AQGR | 20 (40 μL) | 200 μL |
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| SSR1-FARS2-20-AQAQ | 20 (40 μL) | 200 μL |
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SSR1 Gene Summary
The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR consists of 2 subunits, a 34-kD glycoprotein encoded by this gene and a 22-kD glycoprotein. This gene generates several mRNA species as a result of complex alternative polyadenylation. This gene is unusual in that it utilizes arrays of polyA signal sequences that are mostly non-canonical. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2014]
Gene Name: Signal Sequence Receptor Subunit 1
Chromosome: CHR6: 7281287 -7313541
Locus: 6p24.3
FARS2 Gene Summary
This gene encodes a protein that transfers phenylalanine to its cognate tRNA. This protein localizes to the mitochondrion and plays a role in mitochondrial protein translation. Mutations in this gene can cause combined oxidative phosphorylation deficiency 14 (Alpers encephalopathy). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
Gene Name: Phenylalanyl-tRNA Synthetase 2, Mitochondrial
Chromosome: CHR6: 5261583 -5771816
Locus: 6p25.1
Gene Diseases
The SSR1 FARS2 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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