SSPN-TEAD4 Fusion FISH Probe
The SSPN-TEAD4 Fusion FISH Probe is used to confirm a fusion of the SSPN and TEAD4 genes. The fusion of the SSPN and TEAD4 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SSPN-TEAD4-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SSPN-TEAD4-20-RERE | 20 (40 μL) | 200 μL |
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| SSPN-TEAD4-20-REOR | 20 (40 μL) | 200 μL |
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| SSPN-TEAD4-20-REGO | 20 (40 μL) | 200 μL |
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| SSPN-TEAD4-20-REGR | 20 (40 μL) | 200 μL |
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| SSPN-TEAD4-20-REAQ | 20 (40 μL) | 200 μL |
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| SSPN-TEAD4-20-ORRE | 20 (40 μL) | 200 μL |
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| SSPN-TEAD4-20-OROR | 20 (40 μL) | 200 μL |
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| SSPN-TEAD4-20-ORGO | 20 (40 μL) | 200 μL |
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| SSPN-TEAD4-20-ORAQ | 20 (40 μL) | 200 μL |
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| SSPN-TEAD4-20-GORE | 20 (40 μL) | 200 μL |
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| SSPN-TEAD4-20-GOOR | 20 (40 μL) | 200 μL |
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| SSPN-TEAD4-20-GOGO | 20 (40 μL) | 200 μL |
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| SSPN-TEAD4-20-GOGR | 20 (40 μL) | 200 μL |
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| SSPN-TEAD4-20-GOAQ | 20 (40 μL) | 200 μL |
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| SSPN-TEAD4-20-GRRE | 20 (40 μL) | 200 μL |
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| SSPN-TEAD4-20-GROR | 20 (40 μL) | 200 μL |
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| SSPN-TEAD4-20-GRGO | 20 (40 μL) | 200 μL |
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| SSPN-TEAD4-20-GRGR | 20 (40 μL) | 200 μL |
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| SSPN-TEAD4-20-GRAQ | 20 (40 μL) | 200 μL |
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| SSPN-TEAD4-20-AQRE | 20 (40 μL) | 200 μL |
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| SSPN-TEAD4-20-AQOR | 20 (40 μL) | 200 μL |
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| SSPN-TEAD4-20-AQGO | 20 (40 μL) | 200 μL |
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| SSPN-TEAD4-20-AQGR | 20 (40 μL) | 200 μL |
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| SSPN-TEAD4-20-AQAQ | 20 (40 μL) | 200 μL |
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TEAD4 Gene Summary
This gene product is a member of the transcriptional enhancer factor (TEF) family of transcription factors, which contain the TEA/ATTS DNA-binding domain. It is preferentially expressed in the skeletal muscle, and binds to the M-CAT regulatory element found in promoters of muscle-specific genes to direct their gene expression. Alternatively spliced transcripts encoding distinct isoforms, some of which are translated through the use of a non-AUG (UUG) initiation codon, have been described for this gene. [provided by RefSeq, Jul 2008]
Gene Name: TEA Domain Transcription Factor 4
Chromosome: CHR12: 3068477 -3149842
Locus: 12p13.33
SSPN Gene Summary
This gene encodes a member of the dystrophin-glycoprotein complex (DGC). The DGC spans the sarcolemma and is comprised of dystrophin, syntrophin, alpha- and beta-dystroglycans and sarcoglycans. The DGC provides a structural link between the subsarcolemmal cytoskeleton and the extracellular matrix of muscle cells. Two alternatively spliced transcript variants that encode different protein isoforms have been described. [provided by RefSeq, Oct 2008]
Gene Name: Sarcospan
Chromosome: CHR12: 26348268 -26387708
Locus: 12p12.1
Gene Diseases
The SSPN TEAD4 Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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